传染病学精品教学（汕头大学）疟疾ppt课件.pptVIP

疟 疾malaria;概 述;病 原 学 ;Species Infecting Humans;Species Infecting Humans;Morphology and Life Cycle ;Life cycle and Morphology;Development in human body;The sporozoites was injected into human body with the saliva;schizont mature in 6-14 days, the liberation merozoites enter the blood stream. ;The schizonts become mature;The sporozoites that establish in the liver cells are proved of two genetic forms;Bradysporozoite (迟发型子孢子) ;在人体内的发育:红细胞外期;Erythrocytic stage(红内期);Malaria - Merozoite;Malaria – Red blood cell invasion;Malaria – Red blood cell invasion;;P.vivax thin smear, showing early trophozoites. The infected red cells are enlarged and show some stippling.;The entire organism looks like a ruby-ring, which is about 1/3 that diameter of the infected RBC. (In P. vivax); 疟原虫环状体 或裂殖子; 环状体Annular body;The trophozoite (滋养体）;The granules of dark malarial pigment, the metabolite of Plasmodium in digestion of hemoglobin now appears.; ????????????????????????????????????????? ;Schizont (裂殖体）;The number of the nucleus in the mature schizont is 12~24, usually 16. When it matures, its cytoplasm segments to surround every nucleus of it, and the malarial pigment becomes compact;P. vivax thin smear. Merozoites lying free. Malarial pigment is seen as a clump on one side. ; Comparison of four Plasmodium develop in red blood cells 间日疟 恶性疟 三日疟 卵性疟 成熟裂殖体 12-24 8-36 6-12 6-12 中裂殖子数 （16） （18-24） （8） （8） 周期 48h 36-48h 72h 48h 大滋养体 8-10h 10h 24h 8-10h 配子体 4-5天 10-12天 10-12天 5-6天 寄生红细胞 网织红 各期红 较衰老红 网织红 ; ;;;病原学; 疟原虫星月形配子体; 棒形体Club shape body; 香蕉体 banana body;;流行病学;流行病学;Malaria -