作用于血管的降压药物课件.pptVIP

ACCOMPLISH: SBP mmHg Month 5731 5387 5206 4999 4804 4285 2520 5709 5377 5154 4980 4831 4286 2594 Patients ACEI / HCTZ N=5731 CCB / ACEI N=5709 *Mean values are taken at 30 months FU visit 129.3 mmHg 130 mmHg Difference of 0.7 mmHg p0.05* DBP: 71.1 DBP: 72.8 Jamerson K. ACC 2008, Chicago. 基线控制率 37.2 37.9 ACCOMPLISH: 血压控制率 (140/90) ACEI / HCTZ N=5731 控制率 (%) CCB / ACEI N=5709 10 20 30 40 50 60 70 80 90 78.5 81.7 随访30个月时 P0.001 Jamerson K. ACC 2008, Chicago. ACCOMPLISH: 主要终点Kaplan Meier分析 累计事件发生率 （%） HR (95% CI): 0.80 (0.72, 0.90) 风险下降20% CV事件/死亡发生时间 (天) P = 0.0002 ACEI / HCTZ CCB / ACEI