糖尿病药物治疗问题与失误课件.pptVIP

纪立农 北京大学糖尿病中心 北京大学人民医院;2型糖尿病的病因、病理生理和结局;血糖是最难控制的代谢异常;ASCOT: Reductions in Total and LDL Cholesterol;LIIFE 研究---相同的降压疗效;1 2 3 4…; ;Saydah SH et al. JAMA. 2004;291:335-342.;Percentage of Patients With DiabetesHaving A1C 7%;在单药治疗时发现 HbA1c 8.0%后仍然维持单药治疗的时间*（2004年）;0;;多种代谢异常控制的重要性; A tight blood pressure control policy which achieved blood pressure of 144 / 82mmHg gave reduced risk of: 24% for any diabetes-related endpoint p=0.0046 32% for diabetes-related deaths p=0.019 44% for stroke p=0.013 37% for microvascular disease p=0.0092 56% for heart failure p=0.0043 ; UKPDS研究显示：严格降压比强化降糖更重要???