237例子痫前期患者临床资料回顾性分析.docVIP

237例子痫前期患者临床资料的回顾性分析 　　[摘要] 目的 通过分析子痫前期患者的临床资料，比较母婴妊娠结局。 方法 回顾性分析我院产科2013年3月～2014年3月237例子痫前期病例的临床资料，将237例子痫前期患者按照孕周不同分为两组，A组（孕周34周）及B组（孕周≥34周）。比较各组并发症及围产儿结局的发生率。 结果 不同孕周的子痫前期患者并发症以及围产儿妊娠结局的发生情况均不同。两组患者并发症的发生率分别为64.2%、38.8%；新生儿窒息率分别为13.4%、6.5%；围产儿死亡率分别为37.3%、3.6%。 结论 早发型子痫前期患者病情严重，围产儿预后不佳，应严格选择病例进行规范化治疗，密切观察母婴情况，有效控制病情发展，适时终止妊娠。 　　[关键词] 早发型子痫前期；并发症；分娩方式；围产儿结局 　　[中图分类号] R714.2 [文献标识码] B [文章编号] 1673-9701（2015）16-0044-03 　　[Abstract] Objective To compare the pregnancy outcome of mother and infant through the analysis of clinical data of patients with preeclampsia. Methods Clinical data of 237 cases with preeclampsia from March 2013 to March 2014 in the department of obstetrics were analyzed retrospectively. 237 patients with preeclampsia were assigned to two groups according to different gestational weeks， group A （gestational weeks 34 weeks） and group B （gestational weeks ≥34 weeks）. Complications as well as the incidence of outcome of perinatal fetus were compared between groups. Results Complications of patients with preeclampsia and incidence of the pregnancy outcome of perinatal fetus in different gestational weeks were different. Incidence rate of complications in the two groups was 64.2% and 38.8% respectively； neonatal asphyxia rate was 13.4% and 6.5% respectively； mortality rate of perinatal fetus was 37.3% and 3.6%. Conclusion Patients with early-onset of preeclampsia have severe conditions， and the prognosis of perinatal fetus is unfavorable. Cases of disease should be strictly selected and standardized treatment should be carried out. Conditions of mother and infants should be closely monitored， so as to control disease progression effectively and terminate the pregnancy at appropriate times. 　　[Key words] Early onset of preeclampsia； Complications； Delivery mode； Outcome of perinatal fetus 　　妊娠期高血压疾病是妊娠与血压升高并存的一组疾病，发生率约5%～12%。该疾病严重影响母婴健康，是孕产妇和围产儿病死率升高的主要原因。近年来，许多学者提出了早发型重度子痫前期（early onset severe preeclampsia）的概念，而国内外部分学者将发生于34周前的重度子痫前期定义为早发型[1]。国外报道早