二甲双胍联合阿卡波糖对2型糖尿病患者血脂影响临床疗效观察.docVIP

二甲双胍联合阿卡波糖对2型糖尿病患者血脂影响的临床疗效观察 　　摘要：目的 探讨二甲双胍联合阿卡波糖对糖尿病患者血脂水平影响的临床疗效。方法 选取我院2010年~2012年收治的糖尿病患者共90例，依照随机分组法平均分为观察组与对照组，对照组患者予以二甲双胍进行治疗，观察组在对照组基础上联用阿卡波糖治疗，记录并分析两组糖尿病患者在治疗前后的血脂水平的变化情况。结果 对照组患者治疗后胆固醇平均水平（2.45±0.24）mmol/L、三酰甘油平均水平（5.27±0.41）mmol/L、低密度脂蛋白平均水平（3.14±0.39）mmol/L，治疗后各项指标明显低于治疗前（P0.05）。观察组患者治疗后胆固醇平均水平（2.01±0.38）mmol/L、三酰甘油平均水平（4.22±0.24）mmol/L、低密度脂蛋白平均水平（2.08±0.27）mmol/L，治疗后各项指标明显低于治疗前（P0.05）；观察组治疗后各项指标明显低于对照组（P0.05）。结论 联合应用二甲双胍和阿卡波糖治疗2型糖尿病，可保证疗效的同时控制血脂，效果显著，值得在临床上推广应用。 　　关键词：二甲双胍；阿卡波糖；糖尿病；血脂 　　Metformin and Acarbose on Observation of Curative Effect of Blood Lipids in Patients with Type 2 Diabetes 　　HUANG Jin-yan 　　(The Third Peoples Hospital of Nantong City,Nantong 226001,Jiangsu,China) 　　Abstract：ObjectiveTo study the metformin in combination with acarbose on the lipid levels of patients with diabetes mellitus in the clinical curative effect. Methods our hospital from 2010 to 2012 were selected, a total of 90 patients with diabetes, grouping according to randomly divided into observation group and control group, control group patients give metformin treatment, observation group based part in the control group was treated with acarbose, record and analysis of two groups of patients with diabetes in the change of lipid levels before and after treatment. ResultsThe control group after treatment in patients with cholesterol average (2.45 ± 0.24) tendency/L, three acyl glycerin average tendency for L (5.27 ± 0.41), low density lipoprotein (3.14± 0.39) average tendency for L, all the indexes after treatment significantly lower than before treatment (P 0.05). Observation group after treatment in patients with cholesterol average (2.01± 0.38) tendency/L, three acyl glycerin average tendency for L (4.22 ± 0.24), low density lipoprotein (2.08 ± 0.27) average tendency for L, all the indexes after treatment significantly lower than before treatment (P 0.05); Each index after treatment observation group was obviously lower than the control group (P 0.05).Concl