布地奈德联合沙丁胺醇氧气驱动雾化吸入治疗毛细支气管炎的效果观察.docVIP

布地奈德联合沙丁胺醇氧气驱动雾化吸入治疗毛细支气管炎的效果观察 　　[摘要] 目的 探讨布地奈德联合沙丁胺醇氧气驱动雾化吸入治疗毛细支气管炎的临床效果。 方法 将2012年11月～2013年11月住院治疗的102例毛细支气管炎患儿随机分为两组，对照组（50例）给予综合治疗（抗感染、平喘、对症及抗心力衰竭等），治疗组（52例）在综合治疗的基础上给予布地奈德+沙丁胺醇氧气驱动雾化吸入，观察两组患儿的治疗效果。 结果 治疗组治愈率为61.54%，总有效率为94.23%；对照组治愈率为38.00%，总有效率为82.00%；治疗组治愈率和总有效率明显高于对照组，差异有统计学意义（P0.05）。治疗组咳嗽、气促缓解快，喘鸣音、湿??音消失明显，住院时间短，差异有统计学意义（P0.05）。 结论 布地奈德联合沙丁胺醇氧气驱动雾化吸入治疗毛细支气管炎的效果显著。 　　[关键词] 布地奈德；沙丁胺醇；氧气驱动雾化吸入；毛细支气管炎 　　[中图分类号] R725.6 [文献标识码] A [文章编号] 1674-4721（2014）04（b）-0063-03 　　[Abstract] Objective To explore the effect of budesonide combined with salbutamol atomization inhalation of oxygen driven treatment of bronchiolitis. Methods 102 children with bronchiolitis hospitalized in our hospital from November 2012 to November 2013，they were randomly divided into two groups，the control group （50 cases） received comprehensive treatment （anti infection，asthma，symptomatic and anti heart failure），the treatment group （52 cases） with budesonide and salbutamol inhalation driven by oxygen coordination on the basis of comprehensive therapy，the therapeutic effect of two groups of children were obsered. Results The cure rate was 61.54% in treatment group，the total efficiency was 94.23%，the cure rate was 38.00% in control group，the total effective rate was 82.00%，the cure rate and total effective rate was significantly higher than that of the control group respectively，the difference was statistically significant （P0.05）.The cough，shortness of breath was relieved in treatment group，wheezing，wet rales disappeared significantly，shortened hospitalization，the difference was statistically significant （P0.05）. Conclusion The effect of budesonide combined with salbutamol oxygen drive atomization inhalation has significant effect in the treatment of bronchiolitis. 　　[Key words] Budesonide；Salbutamol；Oxygen driven inhalation；Bronchiolitis 　　毛细支气管炎（bronchiolitis）是一种婴幼儿较常见的下呼吸道感染，仅见于2岁以下婴幼儿，多数为1～6个月的小婴儿，其发病与该年龄婴幼儿支气管的解剖学特点有关[1]。以上呼吸道感染为首发症状，继之出现刺激性咳嗽、喘憋、呼吸困难、发热或不伴发热、肺部哮鸣音等，严重者可出现呼吸暂停、呼吸衰竭、心