全身亚低温治疗新生儿重度窒息临床疗效分析.docVIP

全身亚低温治疗新生儿重度窒息临床疗效分析 　　【摘要】 目的：探讨全身亚低温治疗新生儿重度窒息的临床效果。方法：回顾分析2013年4月-2015年4月本院收治的28例重度窒息的新生儿的治疗情况，根据治疗方式，将患儿分为对照组和低温组，分析两组患儿治疗过程中心率、呼吸及收缩压变化情况，治疗后患儿肝、肾、凝血功能变化情况及治疗后的临床转归情况。结果：两组治疗后呼吸及收缩压与治疗前比较，差异均无统计学意义（P0.05），治疗后两组心率均低于治疗前，且低温组心率低于对照组，比较差异均有统计学意义（P0.05）；两组自主吮奶及住院时间比较，差异无统计学意义（P0.05）；低温组NBNA测评得分高于对照组，比较差异有统计学意义（P0.05）。结论：严密监护下采用亚低温治疗新生儿重度窒息能够有效提高临床疗效及预后，无严重不良反应发生，适合在临床上进一步推广。 　　【关键词】 全身亚低温； 新生儿； 窒息； 疗效 　　Clinical Efficacy Analysis of Mild Systemic Hypothermia for Neonates with Severe Asphyxia/DENG Wei-chi.//Medical Innovation of China，2016，13（10）：136-139 　　【Abstract】 Objective：To study the clinical effect of mild systemic hypothermia on newborns with severe asphyxia.Method：The treatment condition of 28 newborns with severe asphyxia in our hospital from April 2013 to April 2015 were retrospectively analyzed.They were divided into control group and hypothermia group according to different treatment methods.The heart rate，breathe and blood pressure of the two groups during therapeutic process were analyzed.The liver function，kidney function，coagulation function after therapy and the clinical outcomes after therapy were also analyzed.Result：The differences in respiratory and blood pressure between before treatment and after treatment were not statistically significant（P0.05）.After treatment，the heart rates of the two groups were lower than before treatment and the heart rate of the hypothermia group was lower than that of the control group，the differences were statistically significant（P0.05）.There were no statistically significant differences in independent sucking milk and hospital stay between the two groups（P0.05）.The NBNA score of the hypothermia group was higher than that of the control group，the difference was statistically significant（P 　　【Key words】 Mild systemic hypothermia； Neonates； Asphyxia； Efficacy 　　First author’s address：Huadu District Maternal and Child Health Hospital of Guangzhou City（Huzhong Hospital），Guangzhou 510800，China 　　doi：10.3969/j.is