厄贝沙坦联合胺碘酮救治心力衰竭并发 室性心律失常临床体会.docVIP

厄贝沙坦联合胺碘酮救治心力衰竭并发 室性心律失常临床体会 　　【摘要】目的对厄贝沙坦联合胺碘酮救治心力衰竭并发室性心律失常的临床效果进行分析探讨。方法将72例心力衰竭并发室性心律失常患者按照随机数表法分为观察组和对照组, 每组36例, 对照组患者使用胺碘酮, 予以强心、利尿及扩张血管等常规治疗, 观察组加用厄贝沙坦, 治疗3个月后, 比较两组患者的血压、心率及临床疗效。结果观察组总有效率为94.4%明显高于对照组77.8%, 差异有统计学意义(P0.05)；治疗后两组患者血压及心率均显著下降, 观察组低于对照组, 差异有统计学意义(P0.05)。结论厄贝沙坦联合胺碘酮救治心力衰竭并发室性心律失常疗效显著, 可有效改善患者心率、血压水平, 值得临床推广应用。 　　【关键词】室性心律失常；胺碘酮；厄贝沙坦 　　 　　Clinical experience of irbesartan and amiodarone in the treatment of heart failure complicated by ventricular arrhythmias WANG Wei-cai, LI Min-ru, YUAN Rui-hao.Department of Emergency, Zhongtang Hospital, Dongguan 523220, China 　　【Abstract】Objective To analyze the clinical effect of irbesartan and amiodarone in the treatment of heart failure complicated by ventricular arrhythmias. Methods Divided 72 cases of patients with heart failure complicated by ventricular arrhythmias were divided into observation group and control group according to a random number table, 36 cases in each group, the control group was treated with amiodarone, cardiac, diuretic and dilation of blood vessels and other conventional treatment, observation group was treated with irbesartan, after 3 months, blood pressure, heart rate and clinical efficacy were compared in two groups. Results Total effective rate of observation group(94.4%) was higher than that of control group(77.8%), there was statistical significance(P0.05); blood pressure and heart rate of two groups were significantly decreased, observation group was lower than control group, there was statistical significance(P0.05). Conclusion Irbesartan and amiodarone have a significant effect in the treatment of heart failure complicated by ventricular arrhythmias which, can improve patient’s heart rate, blood pressure levels effectively and has valuable of clinical application. 　　【Key words】Ventricular arrhythmias; Amiodarone; Irbesartan 　　室性心律失常是导致心力衰竭者死亡的重要原因之一, 患者心力衰竭症状常因未得到及时有效的控制而难以纠正, 对其预后产生严重影响。很多抗心律失常药物均具有负性肌力作用, 如果使用不当则会加重心力衰竭, 因而在治疗心力衰竭并室性心律失常的药物选择方面需格外慎重。据相关研究报道［1］, 厄