右美托咪定在小儿腹腔镜腹股沟疝手术中应用.docVIP

右美托咪定在小儿腹腔镜腹股沟疝手术中应用 　　【摘要】 目的 探?右美托咪定在小儿腹腔镜腹股沟疝手术中对控制苏醒期躁动的作用。 　　方法 40例接受腹腔镜腹股沟疝手术治疗的患儿作为研究对象， 随机分为对照组和观察组， 各20例。观察组在麻醉诱导前给予右美托咪定静脉注射， 对照组在麻醉诱导前给予同等剂量的生理盐水。比较两组患儿的手术时间、麻醉时间、苏醒时间、心率（HR）、平均动脉压（MAP）、躁动发生率及躁动评分。结果 两组患儿的手术时间、麻醉时间、苏醒时间对比， 差异均无统计学意义（t=0.918、-0.276、-0.156， P0.05）。给药后10 min（T1）、术后麻醉清醒时（T2）时间点时， 观察组患儿的HR及MAP均低于对照组， 差异均具有统计学意义（P0.05）。观察组发生苏醒期躁动2例（10.00%）， 躁动评分为（1.79±0.95）分；对照组发生苏醒期躁动8例（40.00%）， 躁动评分为（2.83±1.02）分。观察组苏醒期躁动发生率及躁动评分均低于对照组， 差异均具有统计学意义（P0.05）。结论 右美托咪定在小儿腹腔镜腹股沟疝手术中可显著减少全身麻醉苏醒期躁动的发生， 维持术中血流动力学稳定， 可在临床中推广应用。 　　【关键词】 右美托咪定；小儿腹腔镜；小儿腹股沟疝；苏醒期躁动 　　DOI：10.14163/j.cnki.11-5547/r.2017.33.005 　　Application of dexmedetomidine in pediatric laparoscopic inguinal hernia surgery CHEN Zhi-qiang， LIU Ke-meng， LI Da-xi， et al. Department of Anesthesia， Zhaoqing Traditional Chinese Medicine Hospital， Zhaoqing 526020， China 　　【Abstract】 Objective To discuss the effect of dexmedetomidine on control of restlessness in recovery period during pediatric laparoscopic inguinal hernia surgery. Methods A total of 40 children undergoing laparoscopic inguinal hernia surgery as study subjects were randomly divided into control group and observation group， with 20 cases in each group. The observation group received dexmedetomidine intravenous injection before anesthesia induction， and the control group received same dose of normal saline before anesthesia induction. Comparison were made on operation time， anesthesia time， recovery time， heart rate （HR）， mean arterial pressure （MAP）， agitation rate and agitation score in two groups. Results Both groups had no statistically significant difference in operation time， anesthesia time， recovery time （t=0.918， -0.276， -0.156， P0.05）. At 10 min after administration （T1） and postoperative anesthesia consciousness （T2）， the observation group had lower HR and MAP than the control group， and the difference was statistically significant （P0.05）. The observation group had 2 cases with restlessness in recovery period （10.00%）， and the restl