卷曲霉素联合左氧氟沙星治疗复治涂阳肺结核疗效分析.docVIP

卷曲霉素联合左氧氟沙星治疗复治涂阳肺结核疗效分析 　　[摘要] 目的 探究卷曲霉素联合左氧氟沙星治疗复治涂阳肺结核的疗效，总结临床经验。方法 对照组和观察组患者分别采用3SEL2PaZ/9EL2Pa治疗和在其基础上使用卷曲霉素联合左氧氟沙星治疗，两组患者均为方便选取的该院2013年2月―2015年6月间收治通过治疗方法不同分组而得，并对患者的效果进行观察比较。结果 对比发现观察组患者的肺结核的转阴率（观察组和对照组转阴率分别为92.5%和72.5%）、病灶的吸收率（其中观察组为75.0%，对照组为62.5%）、肺部空洞的闭合率（其中观察组为62.5%，对照组为40.0%）和不良反应发生率（其中观察组为7.5%，对照组为22.5%）均优于对照组，其中经过比较发现差异有统计学意义（P0.05）。结论 对于卷曲霉素联合左氧氟沙星治疗复治涂阳肺结核的疗效进行分析发现，其可以有效减少患者的不良反应，同时改善患者的肺部空洞的闭合情况，使得患者的病灶的吸收率增加，促进患者转阴，对于患者的预后具有十分重要的意义。 　　[关键词] 卷曲霉素；左氧氟沙星；复治涂阳肺结核；疗效 　　[中图分类号] R521 [文献标识码] A [文章编号] 1674-0742（2017）01（b）-0098-03 　　[Abstract] Objective To study the curative effect of capreomycin and Levofloxacin in treatment of recurrent smear-positive pulmonary tuberculosis and summarize the clinical experience. Methods The control group and observation group of patients with 3 sel2paz / 9 el2pa treatment and on the basis of the joint use of capreomycin levofloxacin treatment， two groups of patients are from February 2013 to June 2015 were and by different groups are treatment； And for the patient to observe the effect of comparison. Results The comparison showed that the seroconversion rate of tuberculosis， absorptance of lesions， intrapulmonary cavity closure rate and incidence rate of adverse reactions were better than those in the control group（92.5%， 75.0%， 62.5%， 7.5% vs 72.5%， 62.5%， 40.0%， 22.5%）， and all differences had statistical significance（P0.05）. Conclusion The curative effect of capreomycin and Levofloxacin in treatment of recurrent smear-positive pulmonary tuberculosis is good， which can effectively reduce the adverse reactions of patients， but also improve the closure of intrapulmonary cavity， increase the absorptance of lesions and promote the darkening of patients， which is of important significance to the prognosis of patients. 　　[Key words] Capreomycin； Levofloxacin； Recurrent smear-positive pulmonary tuberculosis； Curative effect 　　肺?Y核在临床中较为多见，患者病情发生往往较难治愈，给患者的正常生活和人际关系均带来一定影响，因为复治涂阳肺结核在临床较为容易传染，因此不断探究并选取相对有效的方法对患者进行治疗是现在共同