厄多司坦对老年支气管扩张症及黏液分泌过多疗效分析.docVIP

厄多司坦对老年支气管扩张症及黏液分泌过多疗效分析 　　[摘要] 目的：探讨厄多司坦治疗患有支气管扩张症及黏液分泌过多的临床效果分析。方法：抽取80例在本院就诊的患有支气管扩张症及黏液分泌过多的老年患者，将其随机分为A、B两组各40例。A组患者采用胸部物理治疗；B组患者在A组基础上采用厄多司坦进行治疗。结果：两组患者在治疗后的VAS评分、MP、MVP、呼吸肌力、用力肺活量、第1秒用力呼气量均较治疗前有明显的改善，差异有统计学意义（P0.05）；B组患者上述指标的改善程度明显高于A组，差异有统计学意义（P0.05）。结论：采用厄多司坦对患有支气管扩张症及黏液分泌过多的老年患者进行治疗的临床效果十分明显，不会造成特殊的严重的并发症和不良反应现象，可以做为今后临床对该类患者进行治疗的首选方法，值得进一步使用和推广。 　　[关键词] 厄多司坦；支气管扩张症；黏液分泌过多；疗效 　　[中图分类号] R974 [文献标识码] A [文章编号] 1674-4721（2012）01（a）-057-02 　　 　　Curative effect analysis of treating senile bronchiectasis and mucus hypersecretion by Erdosteine 　　TANG Yipin 　　Wugang Peoples Hospital of Shaoyang in Hunan Province, Wugang 422400, China 　　[Abstract] Objective: To discuss the clinical effect of treating bronchiectasis and mucus hypersecretion with Erdosteine. Methods: Eighty elderly patients with bronchiectasis and mucus hypersecretion were picked from our hospital and divided into group A and group B randomly, both with a number of 40 cases. Chest physiotherapy was taken for group A, and based on this, erdosteine for group B. Results: Both the groups patients had improved significantly in the VAS score, MP, MVP, RMS, FVC and FEV1 after treatment and with obvious statistical difference (P0.05). In group B, the improvement of the above index was higher than group A apparently with obvious statistical difference (P0.05). Conclusion: The clinical effect is obvious when treating bronchiectasis and mucus hypersecretion with erdosteine for elderly patients, and it cannot cause special or serious complication and adverse reaction. Erdosteine treatment can be the preferred method for such patients in the future, and is worth further use and promotion. 　　[Key words] Erdosteine; Bronchiectasis; Mucus Hypersecretion; Curative Effect 　　 　　支气管扩张症伴慢性气道阻塞的最典型的临床表现为支气管慢性黏液分泌过多、咳嗽、咳痰时间在3个月以上，且连续在2年以上[1]。对于患有老年慢性肺疾病的患者，气道黏液发生堵塞及黏液的高分泌量较大是对预后产生不良影响的主要因素，与肺部感染及其他原因导致的病死率相关[2]。为了对采用厄多司坦对患有支气管扩张症及黏液分泌过多的老年患者进行治疗的临床效果进行比较分析，为今后临床对该类患者进行更有效的治疗，是该病患者的病情在最短时间内得到控制，使患者预后更加理想，提供一些比较有参