一种用于体表外创伤的成膜凝胶剂的研制-贵州科技报告.DOC

一种用于体表外创伤的成膜凝胶剂的研制 （A development of film-forming gel for surface injuries） （起止时间：2015.01.05 至 2018.01.05 ） 目 录 TOC \o 1-2 \h \u HYPERLINK \l _Toc8473 摘 要 PAGEREF _Toc8473 3 HYPERLINK \l _Toc29831 1.研究背景 PAGEREF _Toc29831 5 HYPERLINK \l _Toc5125 2.研究必要性 PAGEREF _Toc5125 5 HYPERLINK \l _Toc10789 3.研究意义 PAGEREF _Toc10789 6 HYPERLINK \l _Toc1068 4.国内外研究进展 PAGEREF _Toc1068 7 HYPERLINK \l _Toc29268 4.1 体表损伤治疗现状 PAGEREF _Toc29268 7 HYPERLINK \l _Toc32463 4.2 凝胶研究现状 PAGEREF _Toc32463 7 HYPERLINK \l _Toc12662 4.3 凝胶剂应用及发展 PAGEREF _Toc12662 8 HYPERLINK \l _Toc14952 5.拟开展研究项目 PAGEREF _Toc14952 10 HYPERLINK \l _Toc336 5.1 项目目标 PAGEREF _Toc336 10 HYPERLINK \l _Toc31249 5.2 研究内容 PAGEREF _Toc31249 10 HYPERLINK \l _Toc3923 5.3 技术流程图 PAGEREF _Toc3923 11 HYPERLINK \l _Toc22831 6.项目进展情况 PAGEREF _Toc22831 11 摘 要 本项目拟与贵州金玖生物技术有限公司合作研制一种用于治疗体表损伤的医疗器械产品——成膜凝胶剂，将其直接涂在创伤表面，形成一层保护膜以隔离或屏蔽创面，有效地防止外界异物再次接触创面而引起疼痛或感染，并促进创口愈合。本项目将从处方配比、生产工艺及质量标准等方面进行研究，通过筛选处方和优化工艺，制备黏附性能良好、物理化学性质稳定、能迅速持久发挥作用的体表用成膜凝胶剂，为临床提供一种安全有效、使用方便、质量可控的体表损伤治疗的新产品，推动我省医疗器械产业发展的步伐，促进地方经济的发展。 关键词：体表；成膜凝胶剂。 Abstract The project intends to Guizhou Jin Jiu Biotechnology Co., Ltd. jointly developed a medical products- film gel for the treatment of surface injuries .which is directly applied to the injuries surface, forming a protective film to isolate or shield wounds, to effectively prevent foreign substances re-exposure to the wound and cause pain or infection and promote wound healing. This project will have a research in prescription ratio, production technology and quality standards, etc., by screening formulation and optimization process for preparing a gel with good adhesion performance, stable physical and chemical properties, can play a role in the rapid and lasting surface .To provide a new product of safe ,effective ,controlled and easy to use in clinical. the pace of the province to promote the development of the medical device industry, promote local economic development. Key words:su