基于结构方程模型2型糖尿病气阴亏虚证实证研究.docVIP

基于结构方程模型2型糖尿病气阴亏虚证实证研究 　　摘要：目的 验证2型糖尿病气阴亏虚证与病因和四诊信息的关系。方法 收集天津市红桥区中医医院和天津医科大学代谢病医院门诊和住院的2型糖尿病患者资料，其中气阴亏虚证185例，其他证型351例。采用Logistic回归分析最大似然估计后退法筛选病因和四诊信息，在此基础上，采用结构方程模型最大似然估计法对2型糖尿病气阴亏虚证与病因和四诊信息的关系进行验证。结果 模型的拟合优度指数（GFI）为0.909，均方根残差（RMR）为0.041，比较拟合指数（CFI）为0.942，表明拟合效果较好，并合理解释了气阴亏虚证与病因和四诊信息之间的关系。结论 从单证候因素角度，利用结构方程模型验证了糖尿病气阴亏虚证与病因和四诊信息的关系。 　　关键词：结构方程模型；2型糖尿病；气阴亏虚证；Logistic回归；症状；病因 　　DOI：10.3969/j.issn.1005-5304.2016.04.008 　　中图分类号：R259.871 文献标识码：A 文章编号：1005-5304（2016）04-0028-04 　　Empirical Study on Qi-yin Deficiency Syndrome of Type 2 Diabetes Based on Structural Equation Model YANG Xiao-nan1， LIU Bao-zhong1， YAN Li-hui2， WANG Hong-wu3， ZHAO Tie-niu3 （1. TCM Hospital of Hongqiao District in Tianjin City， Tianjin 300132， China； 2. Metabolic Disease Hospital， Tianjin Medical University， Tianjin 300070， China； 3. Tianjin University of Traditional Chinese Medicine， Tianjin 300193， China） 　　Abstract： Objective To verify the relationship between qi-yin deficiency syndrome and the etiology and diagnostic information on type 2 diabetes mellitus. Methods Data of 185 cases of qi-yin deficiency syndrome of type 2 diabetes and 351 cases of other syndromes at TCM Hospital of Hongqiao District in Tianjin and Metabolic Disease Hospital of Tianjin Medical University were randomly collected. Etiology and diagnostic information of qi-yin deficiency syndrome were screened by the likelihood radio of forward step method by using Logistic regression analysis. On this basis， the relationship between qi-yin deficiency syndrome and the etiology and diagnostic information was verified by using maximum likelihood estimation method of the structural equation model. Results The goodness of fit index of the model （GFI） was 0.909； root mean square residual （RMR） of that was 0.071； comparative fit index （CFI） of that was 0.942， which suggested that the fitting effect of the model was good. The reasonable interpretation of the relationship between qi-yin deficiency syndrome and the etiology and d