基于文献整理疮疡四畔用药规律研究.docVIP

基于文献整理疮疡四畔用药规律研究 　　[摘要] 目的 基于现代中医外科文献，探讨适用于疮疡四畔的常用药物及外治方剂。 方法 以“超星电子图书数据库”和“中国中医药期刊数据库”作为信息平台，建立疮疡四畔外治药物数据库，应用频数分析、聚类分析等挖掘疮疡四畔的潜方用药规律。 结果 通过对237篇文献的整理，使用频数最多的前10味药物，按频率递减顺序排列分别为黄柏、冰片、大黄、白芷、轻粉、血竭、当归、乳香、麻油、黄连，可见文献中的药物使用比较集中；主要药类为清热药、活血化瘀药，攻毒杀虫止痒药、泻下药、开窍药起辅助作用；得出以金黄散、五味消毒饮为代表的5类常用聚类方。 结论 疮疡的中医外治药物以清热药和活血化瘀药为主，以金黄散、五味消毒饮为代表方剂，通过数据挖掘技术，整体把握疮疡四畔的外治用药规律，为临床研究提供了理论依据。 　　[关键词] 四畔；疮疡；中医外科学；用药规律 　　[中图分类号] R632 [文献标识码] A [文章编号] 1673-7210（2015）09（a）-0096-05 　　[Abstract] Objective To explore suitable for the herbs and external treatment prescriptions of sores perifocal area， based on the modern traditional Chinese medicine surgical literature information. Methods Taking Superstar electronic books database and China Journal of Traditional Chinese Medicine Database as an information platform， drug databases of sores perifocal area was built. The laws of medication about sores perifocal was discussed by data mining of frequency analysis， cluster analysis. Results Through sorting 237 literatures， according to the frequency in descending order， the frequency of the top 10 herbal medicine were cortex phellodendri， borneol， rhubarb， radix angelica dahurica， calomel， dragons blood， angelica， frankincense， sesame oil， coptis， which showed that the drug use was concentrated； the main class was antipyretic drugs， blood circulation drugs. Supporting role was played by poison attack insect antipruritic drug， purgating drug， resuscitation drugs； cluster analysis resulted that five categories of external treatment prescriptions were represented for Jinhuangsan and Wuweixiaoduyin. Conclusion The base herbs are antipyretic drugs， blood circulation drugs. Jinhuangsan and Wuweixiaoduyin represent for external treatment prescriptions. Through data mining techniques， overall grasps the drug laws of sores perifocal area provides the basis for clinical research. 　　[Key words] Perifocal area； Sore； Surgery of Chinese medicine； Drug laws 　　疮疡是一切体表外科疾病的总称，是中医外科疾病中最常见的一大类病证，包括了体表上的肿疡、溃疡、痈、疽、疔疮、疖肿、流注