大株红景天注射液治疗心绞痛临床疗效观察.docVIP

大株红景天注射液治疗心绞痛临床疗效观察 　　[摘要] 目的 观察大株红景天注射液治疗心绞痛的临床疗效。 方法 选取2014年1月～2016年2月我院收治的心绞痛患者120例，将其随机分为治疗组（n=60）和对照组（n=60），对照组予拜阿司匹林、营养心肌、他汀类、钙拮抗剂等药物常规治疗，在常规治疗基础上治疗组加大株红景天注射液10 mL/L.qd，加入250 mL的5%葡萄糖注射液中，疗程10 d，观察临床症状、心电图变化、不良反应及评定临床疗效。 结果 与对照组比较，治疗组临床疗效总有效率明显增高（90.0% vs 63.3%），差异有统计学意义（P0.05）。与对照组比较，治疗组心电图改善总有效率明显增高（80.0% vs 56.7%），差异有统计学意义（P0.05）。 结论 大株红景天注射液对心绞痛具有良好的疗效，是治疗心绞痛的一种有效药物。 　　[关键词] 大株红景天注射液；心绞痛；心电图变化 　　[中图分类号] R259 [文献标识码] B [文章编号] 1673-9701（2016）21-0139-02 　　[Abstract] Objective To observe the clinical efficacy of sofren injection in the treatment of angina pectoris. Methods 120 patients with angina pectoris were selected from January 2014 to February 2016 in our hospital，they were randomly divided into control group（n=60） and treatment group（n=60），the control group was given aspirin， statins， nutrition cardiac， calcium antagonists and other conventional medications. Sofren injection 10 mL/L qd added into 5% glucose solution 250 mL for 10 days was given in the treatment group on the basis of conventional therapy. The clinical symptoms， the electrocardiogram changes and adverse reaction were observed and clinical efficacy was determined. Results As compared with control group，the total efficiency of clinical efficacy in treatment group was significantly higher than that in control group（90.0% vs 63.3%），there was statistical difference of between patients with treatment group and controls（P0.05）. The total efficiency of ECG changes in treatment group was better than that in control group（80.0% vs 56.7%），there was statistical difference between the two groups（P0.05）. Conclusion Sofren injection is a effective drug for treatment of angina pectoris，which has significantly efficacy on angina pectoris. 　　[Key words] Sofren injection；Angina pectoris；Electrocardiogram changes 　　大株红景天属于藏药景天科，具有扩张冠状动脉、改善心肌缺血缺氧及活血化瘀作用，对心绞痛具有一定疗效。心绞痛是冠状动脉粥样硬化性心脏病（冠心病）的常见类型，心绞痛基本病理基础为冠状动脉粥样硬化导致冠状动脉狭窄及冠状动脉痉挛造成的机体出现心肌缺血症状[1]。本研究选择心绞痛患者，以探讨大株红景天注射液临床治疗心绞痛的疗效观察，现报道如下。 　　1 资料与方法 　　1.1 临床资