宫颈电环切术在治疗CINⅡ～Ⅲ级中临床应用.docVIP

宫颈电环切术在治疗CINⅡ～Ⅲ级中临床应用 　　【摘要】 目的 分析在Ⅱ、Ⅲ级宫颈上皮内瘤变（CIN）治疗中宫颈环形电切术（LEEP）的临床应用价值。方法 80例Ⅱ～Ⅲ级CIN患者作为观察对象， 随机将其分为对照组和观察组， 各40例。对照组接受宫颈冷刀锥切术（CKC）治疗， 观察组接受LEEP治疗。对比两组手术时间、术中出血量、住院时间及宫颈愈合时间， 并分析两组术后并发症的发生率。结果 观察组术中出血量明显少于对照组， 手术时间明显短于对照组， 差异有统计学意义（P0.05）。观察组术后并发症发生率明显低于对照组， 差异有统计学意义（P0.05）。结论 LEEP可显著改善Ⅱ～Ⅲ级CIN的手术相关情况， 并降低术后并发症发生率， 值得临床推荐。 　　【关键词】 宫颈上皮内瘤变；宫颈环形电切术；宫颈冷刀锥切术；疗效 　　DOI：10.14163/j.cnki.11-5547/r.2016.09.019 　　Clinical application of loop electrosurgical excision procedure in the treatment of grade Ⅱ～Ⅲ CIN NIE Hui-long， GUO Tian-qi. Department of Gynecology Tumor， Guangdong Zhuhai City Maternal and Child Health Care Hospital， Zhuhai 519000， China 　　【Abstract】 Objective To analyze clinical application value of loop electrosurgical excision procedure （LEEP） in the treatment of grade Ⅱ～Ⅲ cervical intraepithelial neoplasia （CIN）. Methods A total of 80 patients of grade Ⅱ～Ⅲ CIN as observation subjects were randomly divided into control group and observation group， with 40 cases in each group. The control group received cold knife conization （CKC） for treatment， and the observation group received LEEP for treatment. Operation time， intraoperative bleeding volume， hospital stay time， and cervical healing time were compared between the two groups， and their incidences of postoperative complications were analyzed. Results The observation group had much lower intraoperative bleeding volume and shorter operation time than the control group， and the difference had statistical significance （P0.05）. The observation group had much lower incidence of postoperative complications than the control group， their difference had statistical significance （P0.05）. Conclusion LEEP can remarkably improve operation condition for grade Ⅱ～Ⅲ CIN， and reduce incidence of postoperative complications. This method is worth clinical promoting. 　　【Key words】 Cervical intraepithelial neoplasia； Loop electrosurgical excision procedure； Cold knife conization； Curative effect 　　宫颈上皮内瘤变（cervical intraepi