沙美特罗替卡松辅助治疗支气管哮喘效果及对肺功能指标影响.docVIP

沙美特罗替卡松辅助治疗支气管哮喘效果及对肺功能指标影响 　　[摘要] 目的 探究沙美特罗替卡松辅助治疗支气管哮喘的临床效果及对肺功能指标的影响。 方法 选取我院2014年6月～2015年6月收治的支气管哮喘患者共82例，将其随机分为对照组与观察组。对照组应用布地奈德治疗支气管哮喘，观察组在布地奈德治疗基础上应用沙美特罗替卡松辅助治疗。比较两组患者支气管哮喘相关临床症状，如咳嗽、气喘、胸闷等消失时间，支气管哮喘治疗结局及治疗前后患者肺功能相关指标，如用力肺活量（FVC）、呼气峰流速（PEF%）及一秒用力呼气容量/呼气峰流速（FEV1/PEF%）。 结果 观察组患者支气管哮喘相关临床症状消失时间均明显短于对照组，差异有统计学意义（P0.05）。治疗后，观察组患者FVC、PEF%、FEV1/PEF%均高于对照组，差异有统计学意义（P0.05）。 结论 沙美特罗替卡松辅助治疗支气管哮喘有较好的临床效果，可有效提高患者肺功能指标，且无明显不良反应发生，安全可靠，值得临床推广。 　　[关键词] 沙美特罗替卡松；支气管哮喘；肺功能 　　[中图分类号] R974+.3 [文献标识码] A [文章编号] 1674-4721（2016）02（a）-0132-03 　　Effect and impacts on lung function index of salmeterol and fluticas in treating bronchial asthma auxiliary 　　WAN Lin-feng 　　Department of Procurement Section，People′s Hospital of Yichun City in Jiangxi Province，Yichun 336000，China 　　[Abstract] Objective To study the clinical effect and impacts on lung function index of salmeterol and fluticas in treating bronchial asthma auxiliary. Methods 82 bronchial asthma patients from June 2014 to June 2015 of our hospital were selected and randomly into control group and observation group.Patients in control group were treated with budesonide.Patients in observation group were treated with salmeterol and fluticas auxiliary treatment on the basis of budesonide.Bronchial asthma related clinical symptoms liked the disappeared time of cough，pant and chest distress，outcome of bronchial asthma and lung function related index liked FVC，PEF% and FEV1/PEF% before and after treatment were compared. Results The disappeared time of bronchial asthma related clinical symptoms in observation group was obvious shorter than that of control group respectively，and the difference was statistical significance（P0.05）.After treatment，the FVC，PEF% and FEV1/PEF% in observation was higher than that of control group respectively，and the difference was statistical significance（P 　　[Key words] Salmeterol and fluticas；Bronchial asthma；Lung function 　　支气管哮喘是近几年来呼吸内科发病率居高不下的疾病之一，是一种由各种炎性细胞包括嗜酸粒细胞、肥大细胞、中性粒细胞参与的气道高反应性慢性非特异性炎症[1