激光联合微波术在肛门尖锐湿疣疾病中的治疗效果分析.docVIP

激光联合微波术在肛门尖锐湿疣疾病中的治疗效果分析 　　【摘要】目的：观察并比较单纯使用CO2激光、He-Ne激光联合微波术、CO2激光联合微波术治疗肛门尖锐湿疣（CA）患者的临床疗效，探讨临床最佳治疗方案。方法：选取2011年9月至2014年11月期间来我院治疗的178例肛门尖锐湿疣患者作为研究对象。根据自身情况和医生建议，患者选择合适的治疗方案，其中单纯使用CO2激光治疗患者为56人，设为对照组。选择CO2激光联合微波术进行治疗的患者有70人，而另外52位患者选择了He-Ne激光联合微波术进行治疗。分别评估三组患者治疗后创面愈合时间、疼痛指数、治愈率、完全治愈所需次数并进行比较，统计学分析。结果：He-Ne激光联合微波术和CO2激光联合微波术治疗组患者创面愈合所需时间分别为7～9d和7～10d，所需时间少于对照组所需愈合天数10～15d。这三组患者在治疗当天均有不同程度的疼痛，治疗1周、2周、3周之后，He-Ne激光联合微波术组患者疼痛比例分别为4423%、3462%、962%； CO2激光联合微波术治疗组患者疼痛比例分别为4571%、3286%、857%；单纯CO2激光治疗组患者疼痛比例分别为625%、3929%、1786%。这3种治疗方案均出现患者复发现象，治疗3个月之后，对照组、He-Ne激光联合微波术和CO2激光联合微波术复发率分别为3750%、1336%、1286%。对复发患者进行再治疗，对照组所需次数要多于治疗组（He-Ne激光联合微波术或CO2激光联合微波术）。结论：激光联合微波治疗肛周尖锐湿疣疗效较好，是治疗肛周尖锐湿疣较好的手段。 　　【关键词】CO2激光疗法；He-Ne激光；微波术；肛门尖锐湿疣 　　Therapeutic effect of laser combined with microwaves in treating patients with Condyloma Acuminate DU Xianghua1， GU Yuanmin2. 1.Department of Dermatology， Tongcheng People’s Hospital， Xianning 437400， China； 2.Department of Dermatology， Wuhan University People’s Hospital， Wuhan 430060， China 　　【Abstract】Objectives： Investigating a better therapy for curing patients with condyloma acuminate （CA） through comparing the effect of CO2 laser， microwaves combined with CO2 laser， and He-Ne laser. Methods： 178 patients diagnosed with CA from Sep. 2011 to Nov. 2014 in our hospital were selected and divided into different groups according to their therapy： 56 cases of CO2 laser treatment were regarded as control group； 70 patients choosing microwaves combined with CO2 laser and another 52 patients choosing therapy of microwaves combined with He-Ne laser were selected for research. The pain index/cure rate and time used to treat patients in the three groups were recorded and analyzed. Results： The time required for wound healing of microwave combined with He-Ne laser and microwave combined with CO2 laser were 7-9 days and 7-10 days respectively， which were fewer than that of control group （10-15 days）. Before treatment， patients in the 3 groups had varying degrees