引起鼻咽癌患者在放射治疗中发生医院感染危险因素探讨.docVIP

引起鼻咽癌患者在放射治疗中发生医院感染危险因素探讨 　　【摘要】 目的：探析鼻咽癌患者放射治疗期间发生医院感染的危险性因素。方法：将2014年5月-2016年5月笔者所在医院接收的75例鼻咽癌患者作为研究对象，调查分析患者放疗期间医院感染的情况。结果：本组出现程度不同医院感染的患者有60例（80%）；类型包括口腔黏膜感染，皮肤感染，上呼吸道感染；早期鼻咽癌患者感染发生率低于晚期患者，差异有统计学意义（P0.05）；发生医院感染患者口咽黏膜反应程度、放射野皮肤反应程度均高于未发生医院感染患者，平均体质量、血红蛋白量、白细胞总数均低于未发生医院感染患者，差异均有统计学意义（P0.05）。结论：放疗期间鼻咽癌患者发生医院感染的概率较高，危险因素包括皮肤损害、口腔黏膜损害等，亦包括机体免疫力损害与骨髓抑制，需制定出有效积极的预防及控制措施减少医院感染的发生。 　　【关键词】 医院感染； 鼻咽癌； 危险因素； 放射治疗 　　doi：10.14033/j.cnki.cfmr.2018.7.080 文献标识码 B 文章编号 1674-6805（2018）07-0166-03 　　【Abstract】 Objective：To investigate the risk factors of nosocomial infection in patients with nasopharyngeal carcinoma during radiation therapy.Method：A Total of 75 patients with nasopharyngeal carcinoma treated in the ahthor’s hospital from May 2014 to May 2016 were selected as the subjects，and the hospital infection during the period of radiotherapy was analyzed.Result：There were 60 cases of patients with different hospital infections，including oral mucosal infection，skin infection，and upper respiratory tract infection.The incidence rate of early nasopharyngeal carcinoma is lower than that of patients with advanced stage，the difference was statistically significant（P0.05）.The oropharyngeal mucosa reaction degree，radiation field skin reaction degree of patients with hospital infection were higher than patients without hospital infection，the average body mass，hemoglobin content，total number of white blood cells were lower than patients without hospital infection，the differences were statistically significant（P0.05）.Conclusion：During radiotherapy in patients with nasopharyngeal carcinoma，the incidence of hospital infection rate is higher，the risk factors including skin lesions，oral mucosa damage，it also includes immune damage and bone marrow suppression，effective and active prevention and control measures should be developed to reduce the incidence of hospital infection. 　　【Key words】 Hospital infection； Nasopharyngeal carcinoma； Risk factors； Radiotherapy 　　First-author’s addres