新型抗肿瘤药物的研究探究 进展.docVIP

抗肿瘤药物的研究新进展 佚名分享 | 收藏 ? ? 　　摘要　综述和分析了抗肿瘤药物近年来的新进展，包括细胞毒性抗肿瘤药物、以细胞信号转导分子为靶点的抗肿瘤药物、新生血管生成抑制剂、耐药逆转剂、反义药物、端粒酶抑制剂等。　　关键词　抗肿瘤药物；细胞毒性；拓扑异构酶；酪氨酸激酶；法尼基转移酶；血管生成；端粒酶 ABSTRACT　Recent developments and approaches in anti-tumor drug were reviewed and analysed in this manuscript, including new agents of traditional cytotoxity, protein tyrosine kinase inhibitors, farnesyltransferase inhibitors, tumor angiogenesis inhibitors, resistance reversal agents, antisense oligodeoxyribonucleotides, telomerase inhibitors and so forth.　　KEY WORDS　Anti-tumor drug; Cytotoxicity; Topoisomerase; Tyosine kinase; Farnesyltra