振幅整合脑电图在早产儿脑损伤中应用有效性评价.docVIP

振幅整合脑电图在早产儿脑损伤中应用有效性评价 　　【摘要】 目的：探讨振幅整合脑电图（aEEG）在早产儿脑损伤（HIE）中的临床应用及效果。方法：选取2013年3月-2014年3月在本院分娩的40例胎龄28～36周的脑损伤早产儿和18例胎龄28～36周的无脑损伤早产儿，前者为HIE组后者为健康组，在产后48 h内，采用脑电图仪对两组早产儿进行监测，每次连续检测≥2 h。对两组早产儿的振幅整合脑电图（aEEG）进行分析比较，观察其特点与差异。结果：HIE组的aEEG连续性、睡眠觉醒周期、下边缘振幅值比健康组早产儿的相应值低，差异均有统计学意义（P0.05）；且aEEG连续性、睡眠觉醒周期、下边缘振幅值与胎龄相关。结论：振幅整合脑电图异常与早产儿脑损伤具有密切关系，据此，可以及时诊断早产儿是否有脑损伤并且对其病情进行预测。aEEG操作简单、受环境干扰因素少、容易判读在早产儿脑损伤中具有重要临床应用价值。 　　【关键词】 振幅脑整合电图； 早产儿； 脑损伤； 有效性 　　【Abstract】 Objective：To investigate the clinical application and effect of amplitude integrated eleetreencephalogram （aEEG） in the premature infant brain （HIE）.Method：40 cases of brain injury in preterm infants whose gestational age was 28-36 weeks （HIE group）and 18 cases with fetal age of 28-36 weeks premature infants without brain lesion （health group），who were admitted to our hospital in March 2013 to March 2014.In 48 hours after postpartum， infants in the two groups were monitored by electroencephalography，each successive detection ≥2 hours. Amplitude integrated EEG of two groups of preterm infants （aEEG） were analyzed and compared， the characteristics and difference were observed.Result：All the aEEG features were found having significantly lower values in brain injuries group（P0.05）， such as continuty， amplitude of lower bordercontinuty，sleep-wake cycling and all the features have closely association with gestational age.Conclusion：aEEG and brain damage in premature infants has close relationship，therefore，it can timely diagnosis of preterm infants who have brain damage and predict the condition.Because the advantages of simple operation，less affected by environmental factors，easy to read，aEEG has important clinical application value in the preterm infants with brain injury. 　　【Key words】 Amplitude-integrated eleetreencephalogram； Premature infants； Brain injury； Effectiveness 　　First-author’s address：The Sixth People’s Hospital of Nanhai District in Foshan City， Foshan 528248，China 　　doi：10.3969/j.issn.1674-4985.2015.09.04