探讨欣母沛在治疗宫缩乏力产后出血临床效果.docVIP

探讨欣母沛在治疗宫缩乏力产后出血临床效果 　　[摘要] 目的 探讨欣母沛在治疗宫缩乏力产后出血的临床效果。方法 回顾性分析2011年2月―2013年10月在该院因宫缩乏力在胎儿娩出后出血量≥500 mL的80例产妇的临床资料，其中，观察组采用欣母沛治疗，而对照组采用缩宫素治疗，对比两组效果。结果：用药后，观察组总有效率高于对照组 （P0.05），观察组产妇产后1h、2h及24 h内出血量分别为（113.43±58.32）mL、（122.31±48.57）mL、（132.57±63.18）mL，低于对照组 （P0.05），给药后，两组产妇均未出现严重不良反应。结论 采用欣母沛治疗宫缩乏力产后出血具有十分重要的效果，可协同加强子宫收缩程度，减少子宫出血量，促进子宫复旧，有利于提高产妇的生活质量，值得临床应用。 　　[关键词] 欣母沛；宫缩乏力；产后出血；缩宫素 　　[中图分类号] R714.461 [文献标识码] A [文章编号] 1674-0742（2015）05（b）-0126-02 　　Clinical Efficacy of Hemabate on Uterine Inertia for Postpartum Hemorrhage 　　NIE Hong-mei 　　Department of Obstetrics and Gynecology，，the Third People′s Hospital of Henan，Zhengzhou，Henan 450006 China 　　[Abstract] Objective To investigate the clinical efficacy of hemabate on uterine inertia for postpartum hemorrhage. Methods 80 cases of maternal with the bleeding amount ≥500mL after delivery of the fetus due to uterine inertia were included into the study， of which the observation group of 40 cases of maternal with hemabate treatment， and the control group of 40 patients with oxytocin treatment. Results After treatment， the total effective rate of maternal observation group was 95.00%， significantly higher than control group with a significant difference between the groups （P0.05）， in the observation group postpartum 1h， 2h and 24h for the amount of bleeding were （113.43±58.32） mL， （122.31±48.57） mL， （132.57±63.18） mL （P0.05）. No severe side effects were observed in two groups. Conclusion Hemabate for treatment of postpartum hemorrhage with uterine inertia is very important to strengthen the uterine contraction， which can synergistically reduce the amount of bleeding， promote uterine involution， and help improve the quality of life of mothers， and it is worthy of clinical application. 　　[Key words] Hemabate； Uterine inertia； Postpartum hemorrhage； Oxytocin 　　产后出血是指胎儿娩出后24 h内出血量超过500 mL者，一般而言，80%产后出血发生在产后2 h内。产后出血是分娩期严重的并发症（发生率为4%～6%），也是导致孕产妇死亡的四大原因之一[1-2]。其中，宫缩乏力性产后出血在临床上最为常见，严重影响着产妇的健康，甚至威胁着产妇的生命，因此，及时选择强有力的子宫收缩剂是预