探究女性下生殖道性传播病原体感染与输卵管妊娠及预后相关性.docVIP

探究女性下生殖道性传播病原体感染与输卵管妊娠及预后相关性 　　【摘要】目的：分析女性下生殖道性传播病原体感染与输卵管妊娠的相关性，探讨输卵管妊娠术后采用敏感抗生素治疗的效果。方法：将2013年2月至2015年2月于我院行手术治疗的120例输卵管妊娠患者纳入试验组，同期于我院行人工或药物流产的110例健康妊娠女性纳入对照组，分析性传播病原体阳性率与输卵管妊娠发生的相关性，同时将试验组中有生育需求的CT、UU阳性患者纳入观察组，其余纳入预防组，探讨敏感抗生素治疗对患者预后的影响。结果：试验组的CT、UU和CT+UU阳性率分别为19.2%、40.8%和9.2%，均高于对照组的4.5%、17.3%和0.9%，差异有显著性意义（χ2=11.48、15.30、7.91，P0.05）。结论：CT、UU感染与输卵管妊娠的发生有关，采用药敏抗生素治疗患者及其配偶能够有效改善输卵管妊娠患者的预后。 　　【关键词】性传播病原体；输卵管妊娠；预后 　　【Abstract】Objectives： To analyze the correlation between sexually transmitted pathogens infection of female reproductive tract and tubal pregnancy （TP）， to discuss the effect of postoperative sensitive antibiotic treatment. Methods： 120 TP patients in our hospital from February 2013 to February 2015 were selected into the experimental group， while 110 healthy pregnant women conducted artificial or medical abortion were included as the control group， to analyze the correlation between positive rate of sexually transmitted pathogens and TP. CT and UU positive patients with fertility requirements in experimental group were included as observation group while the rest were prevention group， to explore the effect of sensitive antibiotic treatment on the prognosis of patients. Results： The positive rate of CT， UU and CT + UU was 19.2%， 40.8% and 9.2% respectively， higher than the control group of 4.5%， 17.3% and 0.9%， with significant difference （χ2 = 11.48， 15.30， 7.91， P 0.78）. Conclusion： CT and UU infection is associated with the occurrence of TP， and drug sensitive antibiotics for patients and their spouses can effectively improve the prognosis of patients. 　　【Key words】Sexually transmitted pathogens； Tubal pregnancy； Prognosis 　　【中图分类号】R714.2【文献标志码】A 　　异位妊娠又称宫外孕，是一种极为凶险的急腹症，严重威胁着妇女的生命安全。输卵管妊娠（tubal pregnancy，TP）在异位妊娠的发病率中所占比重最大，近年来发病情况更是呈逐年增多、年轻化的趋势[1]。相关文献显示，性传播疾病是输卵管妊娠发生的重要危险因素之一，有性传播疾病史的妇女出现输卵管妊娠的几率是正常女性的14倍，因此探明性传播病原体与输卵管妊娠的相关性对输卵管妊娠发生率的下降有重要意义[2]。当前的研究表明，沙眼衣原体（CT）、解脲支原体（UU）等感染是性传播疾病的主要因素[3]。为此，本研究重点分析了CT、UU等性传播病原体与输卵管妊娠的相关性，并探讨了输卵管妊娠术后采用敏感抗生素