（毕业设计论文）《MPV反应催化合成香茅醇的研究》.doc

PAGE 浙江 * * 学院 毕业设计（论文） 题目：MPV反应催化合成香茅醇的研究 姓　　 名 : 系 别、 专 业 : 导 师 姓 名、职 称 : 完 成 时 间 : MPV反应催化合成香茅醇的研究 摘 要 香茅醇是重要精细有机化学品，可由香茅醛和异丙醇经MPV反应获得。利用分子筛催化剂的选择性，可解决空间位阻较大醛酮化合物MPV反应进行难的问题，实现香茅醛为原料向香茅醇的转化。 课题主要进行分子筛催化剂的制备并应用于催化合成香茅醇的研究。采用气相色谱－质谱联用确定产物结构，气相色谱分析产物含量。以产物的收率和选择性作为考察指标，采用单因素多水平方法，研究了催化剂的活性以及各种因素如反应原料配比，反应温度，反应时间等的影响，确定了合适的工艺条件。最优工艺条件下转化率最高为96.23%，香茅醇的选择性最高为89.17%。此外，对改性分子筛催化剂进行XRD和SEM表征分析。 关键词：香茅醛 香茅醇 MPV反应 催化还原 Abstract Citronellol is an important fine chemical. It can be synthesized with citronellal and isopropanol by Meerwein-Ponndorf-Verley reaction. By using the selectivity of molecular sieve catalyst, the problem of MPV reaction for carbonyl compounds with steric hindrance is easy to resolve. The citronellol was obtained from citronellal. In present work, according to MPV reaction, the synthesis of citronellol over molecular sieve BEA with isopropanol was investigated. The resultant was identified by GC-MS and the content of citronellol was determined by GC. By using the method of single-factor and multi-levels, the yield of citronellol as an index, the effects of catalyst activity including H-BEA, Na-BEA, and Mg-BEA and others conditions such as reactant ratio, reaction temperature, and reaction time was examined to give the preferable process. Under the optimum conditions of catalyst, the maxium conversion of citronellol was 96.23% and the maxium selectivity for citronellol was 89.17%. Furthermore, the catalysts were characterized by XRD and SEM patterns. Key word: citronellal citronellol MPV-reaction catalysis 目 录 TOC \o 1-3 \h \z \u HYPERLINK \l _Toc201352924 摘 要 PAGEREF _Toc201352924 \h I HYPERLINK \l _Toc201352925 Abstract PAGEREF _Toc201352925 \h II HYPERLINK \l _Toc201352927 1 绪论 PAGEREF _Toc201352927 \h 1 HYPERLINK \l _Toc201352928 1.1 课题背景 PAGEREF _Toc201352928 \h 1 HYPERLINK \l _Toc201352929 1.2 课题的目的和意义 PAGEREF _Toc201352929 \h 1 HYPERLINK \l _Toc201352930 1.3 国内外研究现状 PAGEREF _To