营养支持对老年慢性阻塞性肺疾病急性加重期患者临床疗效和生活质量影响.docVIP

营养支持对老年慢性阻塞性肺疾病急性加重期患者临床疗效和生活质量影响 　　[摘要] 目的 探?营养支持对老年慢性阻塞性肺疾病急性加重期（AECOPD）患者临床疗效和生活质量的影响。 方法 选择2016年8～9月在上海市普陀区中心医院收治的老年AECOPD患者62例，按照随机数字表法分为常规治疗组（31例）和营养干预组（31例）。常规治疗组仅给予常规药物治疗，营养干预组在常规治疗组基础上给予营养支持治疗，疗程均为4周。分别采用微型营养评定法（MNA-SF）、COPD评估测试（CAT）、圣乔治呼吸问卷（SGRQ）对治疗前后两组患者的营养状态、急性发作、住院时间及生活质量评分进行比较。 结果 治疗前两组血清白蛋白、前白蛋白、血红蛋白水平及MNA-SF评分比较，差异均无统计学意义（P 0.05），治疗后4周，营养干预组上述指标均明显高于治疗前、治疗后2周及同期常规治疗组，差异均有统计学意义（均P 0.05）。营养干预组住院时间明显短于常规治疗组，差异有统计学意义（P 0.05），治疗后4周，营养干预组CAT评分明显低于常规治疗组，差异有统计学意义（P 0.05）；治疗后4周，两组生活质量各项评分及总分均降低，营养干预组上述评分均显著低于治疗前和常规治疗组，差异均有统计学意义（P 0.05）。 结论 营养支持可改善老年AECOPD患者的营养状况，提高临床疗效及生活质量。 　　[关键词] 慢性阻塞性肺疾病；急性加重期；老年；营养支持；生活质量 　　[中图分类号] R563 [文献标识码] A [文章编号] 1673-7210（2017）11（b）-0104-05 　　[Abstract] Objective To explore the influences of nutrition support on clincial efficacy and quality of life in elderly patients with acute exacerbation of chronic obstructive pulmonary disease（AECOPD）. Methods A total of 62 elderly patients with AECOPD treated in Putuo District Central Hospital of Shanghai from August to September 2016 were randomly divided into conventional treatment group and nutrition intervention group by random number table， with 31 cases in each group. The conventional treatment group was given conventional drug treatment and the nutrition intervention group was given nutrition support for 4 weeks additionally on the bases of conventional treatment group. Short form mini-nutritional assessment （MNA-SF）， COPD assessment test （CAT） and St. George respiratory questionnaire （SGRQ） were used to evaluate the nutritional status， acute episodes， hospitalization and quality of life before and after treatment. Results Before treatment， there were no statistically significant differences in the two groups in the level of ALB， PA，Hb and scores of MNA-SF （P 0.05）. After treatment for 4 weeks， the indicators above in the nutrition intervention group were all higher than those of before treatment， after treatment for 2 weeks and the conventional treatment group， with stat