肾功能与血清hs―CRP在糖尿病慢性肾功能不全患者服用尿毒清颗粒前后水平变化情况分析.docVIP

肾功能与血清hs―CRP在糖尿病慢性肾功能不全患者服用尿毒清颗粒前后水平变化情况分析 　　[摘要] 目的 分析肾功能与血清hs-CRP在糖尿病慢性肾功能不全患者服用尿毒清颗粒前后水平的变化情况。 方法将2012年3月―2013年12月期间该院收治的糖尿病肾病合并慢性肾功能不全的90例患者根据随机数字法分为两组：对照组和实验组各45例，对照组接受基础性支持以及对症治疗，实验组在对照组的基础上给予尿毒清颗粒口服治疗。分别对两组治疗前后的肾功能与血清hs-CRP水平进行测量，并作统计学对比。结果 与治疗前相比，两组患者Alb、SGr以及BUN指数在治疗后均有大幅降低，前后差异具有统计学意义（P0.05）；与对照组相比，实验组患者24 h蛋白尿量以及hs-CRP指数更低，组间差异有统计学意义（P0.05）。结论 对于糖尿病肾病合并慢性肾功能衰竭患者而言，口服尿毒清颗粒较常规基础治疗的临床疗效更佳，患者肾功能与血清hs-CRP水平改善情况更为显著，应在临床推广使用。 　　[关键词] 糖尿病肾病；慢性肾功能不全；高敏-C反应蛋白；尿毒清颗粒；效果 　　[中图分类号] R277 [文献标识码] A [文章编号] 1672-4062（2016）01（b）-0112-03 　　Changes in Kidney Function Before and after Analysis of Serum hs-CRP with Diabetes and Chronic Renal Insufficiency in Patients Taking Niaoduqing Particle levels 　　WANG Yin-hao 　　Department of emergency，the third peoples hospital of Luohe city， Luohe ，Henan Province，462000 China 　　[Abstract] Objective To analyse the changes in kidney function before and after analysis of serum hs-CRP with diabetes and chronic renal insufficiency in patients taking Niaoduqing particle levels. Methods 90 cases of diabetic nephropathy in patients with chronic renal insufficiency in our hospital during March 2012 to December 2013 were divided into the control and experimental group，45 cases in each group. The control group were received basic support and symptomatic treatment， the experimental group were given Niaoduqing particles on basis of the control group. On renal function and serum hs-CRP levels were measured before and after treatment， and were statistically compared. Results Compared with before treatment ， both groups of patients Alb， SGr and BUN index were significantly reduced after treatment ， there was statistical significance（P0.05）； Compared with the control group， the amount of proteinuria in patients with 24h and hs-CRP index were lower in experimental group （P 0.05）. Conclusion Diabetic nephropathy in patients with chronic renal failure， the clinical efficacy of oral granules Niaoduqing was better than conventional basic treatment，re