莫沙比利配合中药治疗胆汁反流性胃炎临床研究.docVIP

莫沙比利配合中药治疗胆汁反流性胃炎临床研究 　　[摘要] 目的 探讨莫沙比利配合中药治疗胆汁反流性胃炎的临床疗效。方法 整群选取2014年12月―2015年12月来该院入院就诊的112例胆汁反流性胃炎患者随机分成治疗组和对照组，每组56例。治疗组：每天餐前30 min服用莫沙比利5 mg，3次/d，配合中药治疗，中药配方：苍术15 g、厚朴15 g、陈橘皮12 g、炙甘草6 g、柴胡12 g、白芍15 g、枳实9 g为主，湿热加黄芩、蒲公英、黄连；气虚加党参、黄芪、白术；脾胃虚寒加吴茱萸、干姜；恶心呕吐剧者加姜半夏，水煎服。对照组：口服吗丁啉10 mg，硫糖铝1 000 mg，餐后1～2 h口服，3次/d。两组疗程均为4周。比较两组治愈率的差异。 结果 治疗组和对照组的治愈率分别为71.43% 和41.07%；总有效率分别为92.86% 和64.29%；两组比较差异有统计学意义（P0.05）。两组不良反应发生率差异有统计学意义（P0.05）。结论 莫沙比利配合中药治疗胆汁反???性胃炎疗效确切。 　　[关键词] 莫沙比利；中西医结合；胆汁反流性胃炎 　　[中图分类号] R259 [文献标识码] A [文章编号] 1674-0742（2017）01（a）-0168-03 　　[Abstract] Objective To investigate the clinical effect of Mosa Billy combined with traditional Chinese medicine in the treatment of bile reflux gastritis. Methods Group selection 112 cases of bile reflux gastritis patients admitted to our hospital from December 2015 to December 2014 were randomly divided into treatment group and control group， 56 cases in each group. The treatment group： before meals every day taking 30min Mosa Billy 5 mg， 3 times daily， with Chinese medicine treatment， traditional Chinese medicine formula： Cangzhu 15 g，Houpo 15 g， Chen Jupi， Magnolia Atractylodes 12 g， licorice 6 g， bupleurum root 12 g， Baishao15 g， Zhishi 9 g of Radix Paeoniae Alba Fructus aurantii， Radix Scutellariae， dandelion， Rhizoma Coptidis and damp heat； Qi deficiency plus Codonopsis， astragalus， Atractylodes； spleen deficiency with Wu Zhuyu ginger， nausea and vomiting； play with ginger pinellia， shuijianbi. Control group： oral domperidone 10 mg， 1 000 mg of sucralfate， postprandial 1 ～ 2 h orally， 3 times a day. The course of treatment was 4 weeks in two groups. The difference of cure rate between the two groups was compared. Results The cure rate of the treatment group and the control group were 71.43% and 41.07% respectively. The total effective rate was 92.86% and 64.29% respectively. There were significant differences between the two groups（P0.05）. There was a significant difference in the incidence of adverse reactions between