苯磺酸氨氯地平片治疗社区高血压临床疗效分析.docVIP

苯磺酸氨氯地平片治疗社区高血压临床疗效分析 　　【摘要】 目的 探讨苯磺酸氨氯地平片治疗社区高血压的临床疗效。方法 98例高血压患者， 随机分为对照组和研究组， 各49例。对照组采用硝苯地平片治疗， 研究组采用苯磺酸氨氯地平片治疗。观察两组治疗效果。结果 两组患者治疗前血压水平比较差异无统计学意义（P0.05）；治??8周后两组患者的血压均低于治疗前， 且研究组患者的血压明显低于对照组， 差异有统计学意义（P0.05）。研究组临床总有效率为95.92%， 高于对照组的83.67%， 差异有统计学意义（P0.05）。研究组患者不良反应发生率为 2.04%， 低于对照组患者的14.29%， 差异有统计学意义（P0.05）。结论 社区高血压应用苯磺酸氨氯地平片治疗具有十分显著的临床疗效， 能够有效降低患者血压， 不良反应少， 值得在临床上大力推广应用。 　　【关键词】 苯磺酸氨氯地平片；高血压；临床疗效 　　DOI：10.14163/j.cnki.11-5547/r.2017.04.008 　　【Abstract】 Objective To explore the clinical curative effect of amlodipine besylate tablets in the treatment of community hypertension. Methods A total of 98 hypertension patients were randomly divided into control group and research group， with 49 cases in each group. The control group received nifedipine tablets for treatment， and the research group received amlodipine besylate tablets for treatment. Treatment effect was compared in two groups. Results There was no statistically significant difference in blood pressure level before treatment （P0.05）. After 8 weeks of treatment， both groups had lower blood pressure than before treatment， and the research group had obviously lower blood pressure than the control group. Their difference had statistical significance （P0.05）. The research group had total clinical effective rate as 95.92%， which was higher than 83.67% in the control group， and the difference had statistical significance （P0.05）. The research group had incidence of adverse reactions as 2.04%， which was lower than 14.29% in the control group， and the difference had statistical significance （P0.05）. Conclusion Amlodipine besylate tablets provides significant clinical curative effect for the treatment of community hypertension， which can effectively reduce the patients’ blood pressure with less adverse reactions. Therefore it is worth clinical promotion and application. 　　【Key words】 Amlodipine besylate tablets； Hypertension； Clinical curative effect 　　本次研究的主要目的是探讨苯磺酸氨氯地平片治疗社区高血压的临床疗效， 选取2013年8月～2015年5月本院门诊接