淫羊藿苷纳米微粒制备及释放性能的分析.docVIP

Study on the Preparation and Release of Icariin nanoparticles Abstract Objective Establishment of the preparation process of icarrin nanoparticles by using the latest nanoparticle materials, followed by checking the icarrin release performance from the nanoparticles in vitro and in vivo. Methods The ICA was separately loaded into the CaCO3 nanoparticles, solid lipid nanoparticles (SLN), and magnetic nano-liposomes (MNL). ICA was loaded into CaCO3 nanoparticles by simply shaking the CaCO3 powder in ICA solution. For ICA-SLN preparation, the ultrasonic emulsification was used coupled with materi