重度子痫前期合并HELLP综合征临床研究.docVIP

重度子痫前期合并HELLP综合征临床研究 　　[摘要] 目的：探讨重度子痫前期合并HELLP（hemolysis elevated lliver enzymes and low platelet count syndrome）综合征患者的临床表现以及诊断治疗。方法：对本院51例重度子痫前期合并HELLP综合征患者的临床资料进行回顾性的分析总结，并就其临床表现，母婴并发症以及分娩的结局进行对比分析。结果：Ⅰ级组22例HELLP综合征的患者在LDH、临床并发症的发生率以及围生儿的死亡率方面均明显的高于Ⅱ级组29例患者（P＜0.05）。结论：临床HELLP综合征为重度妊娠高血压严重的并发症，并且相对于Ⅱ级HELLP综合征而言，Ⅰ级的临床病情更为严重，因而要进行及时的诊治，适时予以终止妊娠，方可降低母婴的死亡率。 　　[关键词] 妊娠期高血压疾病；重度子痫前期；妊娠高血压综合征；并发症 　　[中图分类号] R714.24+5 [文献标识码]A[文章编号]1674-4721（2011）07（a）-042-02 　　 　　Clinical research of severe preeclampsia HELLP syndrome 　　YAO Jin 　　The First People′s Hospital of Loudi City, Hunan Province, Loudi 417009, China 　　[Abstract] Objective: To investigate the combination of severe preeclampsia and HELLP (hemolysis elevated lliver enzymes and low platelet count syndrome) and clinical manifestations of patients with the diagnosis and treatment. Methods: 51 cases in our hospital of severe preeclampsia HELLP syndrome combined clinical data were retrospectively analyzed and summarized, and on its clinical presentation, maternal complications and birth outcomes were compared. Results: Ⅰ-class group of 22 patients with HELLP syndrome in patients with LDH, the incidence of clinical complications and perinatal mortality rates were significantly higher than grade Ⅱ group of 29 patients (P0.05). Conclusion: Clinical HELLP syndrome, a serious complication of severe pregnancy-induced hypertension and HELLP syndrome compare in terms of grade Ⅱ, Ⅰ grade more severe clinical illness, and thus to timely diagnosis and treatment, to be timely termination of pregnancy before reduce maternal and infant mortality. 　　[Key words] Pregnancy induced hypertension; Severe preeclampsia; HELLP syndrome; Complications 　　 　　临床HELLP综合征为重度妊娠高血压严重的并发症[1]。本文对本院51例重度子痫前期合并HELLP综合征患者的临床资料进行了回顾性的分析总结，并就其临床表现，母婴并发症以及分娩的结局做了相关对比分析。现将具体研究结果报道如下： 　　1 资料与方法 　　1.1 一般资料 　　选取2000年3月～2010年7月本院产科所确诊的51例重度子痫前期合并HELLP综合征孕妇，年龄为22～38岁，平均（28.73±4.90）岁；孕周为28～42周，平均（30.9±5.0）周。孕妇均存在不同程度的头昏、头痛、眼花以及视物模糊；伴水肿、蛋白尿、不同程度高血压；Ⅰ级组的