醒脑静注射液联合阿托伐他汀钙胶囊治疗急性脑出血临床效果分析.docVIP

醒脑静注射液联合阿托伐他汀钙胶囊治疗急性脑出血临床效果分析 　　[摘要] 目的 观察醒脑静注射液联合阿托伐他汀钙胶囊治疗急性脑出血的临床效果。 方法 采用随机数字表法进行分组，将我院从2016年9月～2017年9月收治的100例急性脑出血患者随机分为研究组和对照组，每组各50例。对照组患者予20 mg阿托伐他汀钙胶囊进行治疗，口服，每日1次，研究组患者在对照组的基础上予静脉滴注20 mL醒脑静注射液治疗，每日2次，两组的疗程时间均为50 d。对比观察两组患者的临床疗效与不良反应发生情况。 结果 研究组治疗总有效率为96%；对照组治疗总有效率为70%。研究组总有效率显著高于对照组，研究组的不良反应发生率（6%）明显少于对照组（20%），两组差异有统计学意义。治疗前，研究组CRP为（10.55±0.87）mg/L，IL-1β为（10.36±0.77）ng/L，对照组的对应数据为（12.79±1.28）mg/L、（11.98±1.36）ng/L，两组差异无统计学意义；治疗后，两组差异有统计学意义。 结论 醒脑静注射液联合阿托伐他汀钙胶囊治疗急性脑出血的效果显著，值得应用。 　　[关键词] 醒脑静注射液；阿托伐他汀钙胶囊；急性脑出血；不良反应 　　[中图分类号] R743.34 [文献标识码] B [文章编号] 1673-9701（2018）03-0097-03 　　Clinical efficacy of combing Xingnaojing injection with atorvastatin calcium capsules in patients with acute cerebral hemorrhage 　　SUN Meifen Zhou Lili 　　Department of Neurology， the Third Peoples Hospital of Heze in Shandong Province， Heze 274000 ， China 　　[Abstract] Objective To investigate the clinical efficacy of combing Xingnaojing injection with Atorvastatin calcium capsules in patients with acute cerebral hemorrhage. Methods A total of 100 patients with acute cerebral hemorrhage in our hospital from September 2016 to September 2017 were randomized into the study group and the control group by random number table， with 50 patients in each. Patients of the control were treated with oral atorvastatin calcium capsules 20 mg once per day. Patients in the study group were treated with additional Xingnaojing injection 20 mL by intravenous infusion twice per day. The duration of treatments was 50 days. Clinical efficacy and adverse effects were observed and compared in two groups. Results The rate of efficacy in the study group（96%） was significantly higher than that in the control group （70%）. The rate of adverse effects in the study group（6%） was statistically less than that in the control group（20%）. There were no differences of the levels of CRP and IL-Iβ in the study and control groups before treatment [study group： （10.55±0.87）mg/L， （10.36±0.77）ng/L vs Control group： （12.79±1