Sedation of Patients in the Intensive Care Unit幻灯片.pptVIP

Copyright restrictions may apply. Riker, R. R. et al. JAMA 2009;301:489-499. Safety Outcomes During Treatment With Dexmedetomidine vs Midazolam Cost minimization Median cost savings of $9700 (95% CI $2300-$17000) 2/3 from decreased ICU LOS and 1/3 from decreased MV) Dex: $50 for 200 mcg vial Midazolam $1.56 for 5 mg vial Dasta CCM Feb 2010 Combining sedation and ventilator weaning protocols 336 MV patients in 4 hospitals Sedation awakening trial (SAT) + SBT vs usual sedation + SBT Non-protocolized sedation practice Main outcome: days alive and free of MV up to 28th day Girard Lancet 371:126