47例脑小血管病患者脑血流动力学与认知功能损害地相关性研究.pdfVIP

International Journal of Psychiatry and Neurology 国际神经精神科学杂志, 2016, 5(4), 63-69 Published Online November 2016 in Hans. /journal/ijpn /10.12677/ijpn.2016.54011 Correlation of Cerebral Hemo-Dynamics and Cognitive Function of 47 Patients with Cerebral Small Vessel Diseases * * # Yan Wang , Yijuan Wang , Xiaoxia Hu, Ru Hao, Tong Yong, Cai Wei, Jun Yang Department of Gerontology, Xinjiang U rumqi Military General Hospital, Urumqi Xinjiang th th th Received: Oct. 27 , 2016; accepted: Nov. 15 , 2016; published: Nov. 18 , 2016 Copyright © 2016 by authors and Hans Publishers Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). /licenses/by/4.0/ Open Access Abstract Objective: To explore the correlation of cerebral hemo-dynamics and cognitive function in pa- tients with cerebral small vessel diseases (CSVD). Methods: Clinical data were collected in consec- utive patients who visited the gerontology department in Xinjiang Urumqi Military General Hos- pital from June 2015 to March 2016 and were diagnosed with CSVD after exclusion of large cere- bral vascular disease by CTA or MRA. Cerebral hemo-dynamics were assessed using Transcranial Doppler, while cognitive function was assessed by neuropsychological scale and event-related po- tential. Then the correlations were analyzed. Results: Of the 47 patients included, 80.9% were male, aged 65.17 ± 10.68 years. Cognitive function in Montreal Cognitive Assessment (MOCA) was mildly abnormal with scores of 23.70 ± 5.46, and Mini-Mental State Examination (MMSE) scores