ICU重症感染患者抗菌治疗前后痰培养病原菌动态变化和临床疗效分析.docVIP

ICU重症感染患者抗菌治疗前后痰培养病原菌动态变化和临床疗效分析 　　摘要：目的 分析ICU重症感染患者抗菌治疗的临床效果，以及痰培养病原菌的动态变化。方法 选择2014年1月～2016年6月我院收治的80例ICU重症感染患者，随机将其分为对照组（常规治疗）和试验组（针对性抗菌治疗）各40例，观察临床疗效，比较治疗前后痰培养病原菌的变化情况。结果 80例患者痰培养病原菌种类以鲍氏不动杆菌、铜绿假单胞菌、大肠埃希菌为主，治疗后病原菌数量明显降低。试验组治疗有效率为92.50%，高于对照组的75.00%；且患者高温、咳嗽、咳痰症状消失时间均短于对照组，差异有统计学意义（P0.05）。结论 ICU重症感染患者实施抗菌治疗具有良好效果，能够减少痰培养病原菌数量，缩短症状消失时间，值得临床推广。 　　关键词：ICU；重症感染；抗菌治疗；病原菌 　　中图分类号：R459.7 文献标识码：A 文章编号：1006-1959（2017）21-0064-02 　　Dynamic Changes and Clinical Efficacy of Sputum Culture Pathogens in Patients with Severe ICU Infection before and after Antimicrobial Treatment 　　XIAO Jian 　　（Department of Intensive Medicine，Peoples Hospital of Pengshan District，Meishan 620000，Sichuan，China） 　　Abstract：Objective To analyze the clinical effect of treatment of patients with antibiotic ICU of severe infection，and dynamic change of sputum culture for pathogens.Methods From January 2014 to June 2016，in our hospital 80 cases of patients with severe ICU infection，were randomly divided into control group（routine treatment）and experimental group（targeted antimicrobial therapy）40 cases，observation the clinical efficacy，changes before and after treatment of sputum culture pathogens.Results 80 cases of patients with sputum culture for pathogens to Acinetobacter baumannii，Pseudomonas aeruginosa，Escherichia coli，after treatment significantly reduced the amount of pathogenic bacteria.The experimental group cure rate was 92.50%， higher than 75.00% in the control group；and with high temperature，cough，sputum symptoms disappeared time was shorter than the control group，the difference was statistically significant（P0.05）.Conclusion ICU severe infection patients with antibacterial treatment has good effect，can reduce the number of pathogenic bacteria in sputum culture，shorten the time of disappearance of symptoms，and is worthy of clinical promotion. 　　Key words：ICU；Severe infection；Antimicrobial therapy；Pathogenic bacteria 　　ICU患者?l病急、病情重，多伴有器官功能损害，而且病情进展快。临床治疗期间，需要气管插管等侵入性操作，并给予器官功能支持，因此