血浆超敏C反应蛋白和急性冠脉综合征患者冠脉疾病程度分析.docVIP

血浆超敏C反应蛋白和急性冠脉综合征患者冠脉疾病程度分析 　　DOI：10.16662/j.cnki.1674-0742.2017.09.034 　　[摘要] 目的 探讨急性冠脉综合征（ACS）患者冠脉病变程度与血浆超敏C反应蛋白（hs-CRP）指标之间的关系。方法 方便选择该院自2014年5月―2016年5月间收治的急性冠脉综合征患者84例进行研究，对比急性心肌梗死患者（AMI）45例、不稳定性心绞痛（UAP）患者39例血液中hs-CRP水平的差异，分析不同病情程度hs-CRP的相关性。 结果 ACS患者中UAP组患者的Hs-CRP指标为（5.01±1.84）mg/L， Gensini评分为（36.42±23.80）分；而AMI组患者两项指标依次为（6.36±2.40）mg/L，（43.48±25.33），组间数据对比差异有统计学意义（P0.05）。 结论 急性冠脉综合征冠脉病变严重程度与血浆超敏C反应蛋白存在相关性，能够准确反映心肌受损情况，为疾病诊断治疗提供指导。 　　[关键词] 急性冠脉综合症；超敏c反应蛋白；Gensini评分 　　[中图分类号] R54 [文献标识码] A [文章编号] 1674-0742（2017）03（c）-0034-03 　　Analysis of Correlation between the Hypersensitive C-reactive Protein and Coronary Disease Degree of Patients with Acute Coronary Syndrome 　　LIU Miao， CHEN De-chun， BAI Xu-chen 　　First Department of Cardiovascular Medicine， Tuohua First Hospital， Tuohua， Heilongjiang Province， 152000 China 　　[Abstract] Objective To study the correlation between the hypersensitive C-reactive protein and coronary disease degree of patients with acute coronary syndrome. Methods 84 cases of patients with acute coronary syndrome admitted and treated in our hospital from May 2014 to May 2016 were conveniently selected for research， and the difference in the hs-CRP level in blood of 45 cases of AMI patients and UAP patients was compared and the correlation of hs-CRP of different disease degrees was analyzed. Results The differences in the Hs-CRP index and Gensini score between the UAP patients in ACS patients and AMI patients were statistically significant by comparison[（5.01±1.84）mg/L， （36.42±23.80）points vs （6.36±2.40）mg/L，（43.48±25.33）]（P0.05）. Conclusion There is a correlation between the severity of acute coronary syndrome and hypersensitive c-reactive protein， which can reflect the cardiac muscle injury situation and provide guidance for the disease diagnosis and treatment. 　　[Key words] Acute coronary syndrome； Hypersensitive c-reactive protein； Gensini score 　　急性冠?}综合症（Acute coronary syndrome，ACS）是临床上发病率较高且病情较为严重的心血管疾病，其病因多因为冠状动脉粥样硬化板块发生侵袭或者破裂继