小儿手足口病并暴发性心肌炎4例临床治疗的研究.docVIP

小儿手足口病并暴发性心肌炎4例临床治疗的研究 　　【摘要】 目的： 探讨小儿手足口病并暴发性心肌炎的临床治疗效果。方法：选择近期笔者所在医院收治的4例小儿手足口病并暴发性心肌炎患儿，首先对所有患儿进行常规治疗，之后根据具体病情给予患儿布洛芬、维生素及更昔洛韦治疗，观察治疗前后变化并分析疗效。结果：所有患儿病情得到明显改善，临床症状基本消失，心电图基本恢复正常，血清肌酸激酶同工酶（CK-MB）为（25.47±15.23）U/L、乳酸脱氢酶（LDH）为（54.45±32.46）U/L，较治疗前（59.76±19.38）、（217.22±54.26）U/L显著下降（P0.05）。结论：采用对症治疗的方法治疗小儿手足口病并暴发性心肌炎患儿，不仅能够提高患儿的病愈率，还能增强患儿的身体素质，治疗效果显著，值得临床推广应用。 　　【关键词】 小儿手足口病； 暴发性心肌炎； 治疗效果 　　中图分类号 R725.1 文献标识码 B 文章编号 1674-6805（2015）4-0116-03 　　Clinical Efficacy Study on the Treatment of Four Cases of Children with Hand Foot and Mouth Disease Complicated by Fulminant Myocarditis/FAN Hua-qing.//Chinese and Foreign Medical Research，2015，13（4）：116-118 　　【Abstract】 Objective：To investigate the clinical efficacy of the treatment of children with hand foot and mouth disease complicated by fulminant myocarditis.Method：4 cases of children with hand foot and mouth disease recently received in our hospital，firstly we adopted the routine treatment and the administered ibuprofen，vitamins and ganciclovir to the children based on their detailed conditions，observed the changes and analyzed the efficacy.Result：4 cases got improved，clinical symptoms almost disappeared and their ECG returned to normal.Besides，the serum creatine kinase isoenzyme（CK-MB） was （25.47±15.23）U/L and lactate dehydrogenase（LDH） was （54.45±32.46）U/L，which were lower than those of before treatment[（59.76±19.38）U/L，（217.22±54.26）U/L，P0.05].Conclusion：The use of symptomatic treatment in children with hand foot and mouth disease complicated by fulminant myocarditis can effectively improve the the cure rate and their physical fitness，and the efficacy is significant，is worthy of clinical promotion and application. 　　【Key words】 Children with hand foot and mouth disease； Fulminant myocarditis； Efficacy 　　First-author’s address：Machong Hospitals of Dongguan City，Dongguan 523142，China 　　doi：10.14033/j.cnki.cfmr.2015.04.057 　　手足口病（hand foot and mouth disease，HFMD）是一种由肠道病毒引起的急性传染病，多见于5岁以下儿童。致病肠道病毒种类多达20余种，以肠道病毒71型