强筋壮骨丸辅助经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折临床的研究.docVIP

强筋壮骨丸辅助经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折临床的研究 　　摘要：目的 ?^察强筋壮骨丸辅助经皮椎体后凸成形术（PKP）治疗骨质疏松性椎体压缩骨折（OVCF）的临床疗效。方法 采用随机数字表法将68例OVCF患者分为对照组和治疗组各34例。2组均行PKP，术后予碳酸钙/维生素D3片，每日600 mg，口服，不少于6个月。治疗组在上述治疗基础上予强筋壮骨丸，每次6 g，每日3次，口服，连续治疗12个月。观察2组治疗前及术后1、6、12个月的疼痛视觉模拟评分（VAS）、Oswestry功能障碍指数评分（ODI）、伤椎椎体前缘高度、腰椎骨密度（BMD）及并发症。结果 与本组术前比较，2组术后1、6、12个月VAS、ODI、伤椎前缘高度均明显改善（P0.05）。结论 强筋壮骨丸辅助PKP治疗OVCF可改善患者疼痛，提高生活质量，增加椎体BMD。 　　关键词：强筋壮骨丸；骨质疏松；椎体压缩性骨折；经皮椎体后凸成形术 　　DOI：10.3969/j.issn.1005-5304.2018.05.008 　　中图分类号：R274.91 文献标识码：A 文章编号：1005-5304（2018）05-0032-04 　　Clinical Study on Qiangjin Zhuanggu Pills Combined with PKP Therapy for Treatment of Osteoporotic Vertebral Compression Fractures 　　YUE Jin， YIN Pei-yu， HAN Ting-liang， YANG Qi-jin， WANG Guo-jun 　　Traditional Chinese Medicine Hospital of Yancheng City Affiliated to Nanjing University of Chinese Medicine， Yancheng 224001， China 　　Abstract： Objective To study the clinical efficacy of Qiangjin Zhuanggu Pills combined with percutaneous kyphoplasty （PKP） therapy on osteoporotic vertebral compression fracture （OVCF）. Methods Totally 68 OVCF patients were randomly divided into control group and treatment group， with 34 cases in each group. Both groups were treated by PKP and received oral vitamin D3 and caltrate daily， while those in the treatment group were given Qiangjin Zhuanggu Pills additionally， once 6 g， three times a day， orally， for twelve months. Before and in 1， 6， and 12 months after the surgery， visual analogue scale （VAS）， Oswestry disability index （ODI）， the height of the anterior border of vertebral bod， BMD of the lumbar spine and complications in the two groups were observed and compared. Results Compared with before the treatment， patients in the two groups showed significant improvements in the VAS， ODI and vertebral height 1， 6， and 12 months after the surgery （P0.05）； During 6， and 12 months after the treatment， compared with the control group， the treatment group showed notable increases in the VAS， ODI， vertebral height and BMD of the