多发性骨髓瘤预后因素的临床研究内科学专业论文.docxVIP

宁夏医科大学硕士研究生学位论文英文摘要 宁夏医科大学硕士研究生学位论文 英文摘要 II II Prognostic factors in multiple myeloma clinical research ABSTRACT Objective Analyze the prognostic factors for multiple myeloma（multiple myeloma， MM）. Methods Collected from August 2002 to July 2009 in Ningxia Medical University Hospital diagnosed cases of MM patients information on the relevant data collation, analysis. Result 1.Younger than 60 years survival of patients older than 60 years than in patients with longer survival.2. Male and female survival of MM patients were statistically no significant difference.3. Hemoglobin greater than 100g / L survival of MM patients with hemoglobin less than or equal than 100g / L in MM patients with longer survival.4. Normal platelet survival in MM patients with reduced platelet survival in MM patients over a long period.5. Renal survival in patients with normal renal function compared with a longer survival in patients with damage.6. Survival of MM patients without bone damage is longer than survival of MM patients with bone damage.7. Plasma cell percentage less than 15% survival of MM patients with plasma cell percentage of 15% survival of MM patients were statistically no significant difference.8. IgG level of less than 70g / L Patients with shorter survival compared to IgG levels greater than 70g / longer survival of patients, IgA level less than 50g / L Patients with shorter survival compared to IgA levels greater than 50g / L in patients with longer survival.9. Albumin in patients with normal albumin decreased survival compared to patients with longer survival.10. The higher the level of β2-microglobulin in patients with shorter survival.11. Normal LDH in MM patients with LDH increased survival compared to patients with longer survival.12. Logistic regression analysis showed that age more than 60 years of age, thrombocytopenia, bone destruction, β2-MG 5.5 mg / L, albumin reduction is independent of MM survival factors.13.VAD and thalidomide with chemotherapy PAGE PAGE