层层组装法构筑水滑石无酶葡萄糖传感器的研究分析化学专业论文.docxVIP

Ab Abstract I I THE STUDY OF LAYERED DOUBLE HYDROXIDE-BASED NONENZYMATIC GLUCOSE SENSOR PREPARED BY LAYER-BY-LAYER SELF-ASSEMBLY METHOD ABSTRACT This paper mainly studied the layered double hydroxides(LDH)-based nonenzymatic glucose sensor constructed by layer-by-layer(LBL) self-assembly method, mainly including four parts as follows: This paper synthesized cobalt aluminium layered double hydroxides (CoAl-LDH) and nickel aluminum layered double hydroxides (NiAl-LDH) by co-precipitation, which were characterized by using X ray diffraction spectrum, infrared spectrum and SEM. The multilayer film electrode was prepared by electrostatic LBL self-assembly of negatively charged polystyrene sulfonate sodium (PSS) and positively charged CoAl-LDH, which can detect glucose due to the reversible Co(III)/Co(II) redox activity center of CoAl-LDH in alkaline condition. UV–Vis spectroscopy was used to monitor the uniform LBL self-assembly of CoAl-LDH and PSS. Electrochemical study discussed the effects of different layers on the sensor electrochemical behaviour, and the performance of electrocatalytic oxidation glucose with the multilayer film electrode was studied. The linear response range of the sensor to the glucose is 5.0×10–6~6.63×10–4mol/L, the sensitivity is up to 4.96× 10–4A.L.mol-1,correlation coefficient is 0.9999, detection limit is 2.8×10–6mol/L(S/N=3). The PSS/NiAl-LDH multilayer film electrode was constructed by LBL self-assembly method, which can detect glucose due to the reversible Ni(III)/Ni(II) redox activity center of NiAl-LDH in alkaline condition. UV–Vis spectroscopy was used to monitor the uniform LBL self-assembly of NiAl-LDH and PSS. Electrochemical study discussed the effects of different layers on the sensor electrochemical behaviour, and the performance of electrocatalytic oxidation glucose with the multilayer film electrode was studied. The linear response range of the sensor to the glucose is 5.0×10–7~6.61×10–4mol/L, the sensitivity is up