分子生物学张海红chapter17.ppt

A histone code Different patterns of modification on histone tails can be “read” to mean different things. The “meaning” would be the result of the direct effects of these modifications on chromatin density and form. But in addition, the particular pattern of modifications at any given location would recruit specific proteins. Modification of the histone N-terminal tails alters the function of chromatin Histone modification and the histone code hypothesis Transcription can also be silenced by methylation of DNA by enzymes called DNA methylases. This kind of silencing is not found