细辛脑注射液治疗小儿毛细支气管炎的的疗效观察.docVIP

细辛脑注射液治疗小儿毛细支气管炎的的疗效观察 　　[摘要] 目的 探索细辛脑注射液治疗小儿毛细支气管炎的临床疗效。 方法 将200例患儿随机分为两组，对照组90例予以抗感染、止咳、平喘等常规治疗，治疗组110例在常规治疗的基础上予以细辛脑注射液0.4~0.5 mg/（kg?d）静滴，用5%~10%葡萄糖注射液稀释后静滴，每日1次，疗程5~7 d。 结果 治疗组呼吸道症状、体征的缓解，退热及缩短病程均优于对照组（P ＜ 0.01），治疗组总有效率为95.45%，对照组总有效率为85.55%，治疗组明显优于对照组（P ＜ 0.01）。 结论 细辛脑注射液治疗小儿毛细支气管炎疗效确切，安全可靠。 　　[关键词] 小儿毛细支气管炎；细辛脑注射液；中药；疗效 　　[中图分类号] R725.6 [文献标识码] A [文章编号] 1674-4721（2012）02（b）-0113-02 　　 　　Clinical effect of asarone injection in the treatment of children bronchiolitis 　　GUO Yunwei 　　The General Hospital of Yongmei Group in Henan Province, Yongcheng 476600, China 　　[Abstract] Objective To explore the clinical curative effect of asarone injection in bronchiolitis． Methods Two hundred cases of children with bronehiolitis were randomly divided into two groups. The control group (n = 90) were given comprehensive treatment such as anti-infective, anti-virus, anti-asthmatic and so on. The treatment group (n = 110) used asarone injection 0.4-0.5 mg/(kg?d), 5％ or 10％ of the diluted glucoge injection, intravenous drip, once a day, for the course of 5 to7 days. Results Respiratory tract symptoms and signs of remission, fever and the shortening the couese in the treatment group were better than the control group (P ＜ 0.01), the total effective rate of the treatment group in 95.45% was significantly better than the control group in 85.55% (P ＜ 0.01). Conclusion Use of assrone injection in the treat-ment of bronchiolitis has good efficacy and it is safe, precise and reliable． 　　[Key words] Asarone; Bronchiolitis; Traditional Chinese medicine; Effect 　　 　　毛细支气管炎是小儿时期常见的呼吸道感染疾病，以冬春严寒季节多发，婴幼儿发病率最高，严重影响小儿健康。本科自2009年1月以来采用细辛脑注射液治疗小儿毛细支气管炎，取得了良好的疗效，现报道如下： 　　1 资料与方法 　　1.1 一般资料 　　200例均为2009年1月～2011年11月在本科住院患儿，均符合文献[1]相关诊断标准，以咳喘、发热为主症，肺部听诊可闻及干湿?音，X线胸片提示肺部实性改变，随机分为两组。治疗组110例，男56例，女54例；年龄6个月～3岁，平均1.6岁，发病时间1～7 d，平均2 d，体温 ＞ 39℃ 14例，38～39℃ 40例，＜ 38℃ 56例；对照组90例，男48例，女42例；年龄6个月～3岁，平均1.6岁，发病1～7 d，平均2.5 d，体温＞ 39℃ 12例，38～39℃ 42例，＜ 38℃ 36例。两组性别、年龄及病程、病情大致分布一致，差异无统计学意义（P ＜ 0.01）。