联合的应用低分子肝素钙酚妥拉明治疗肺心病顽固性心力衰竭临床观察.docVIP

联合的应用低分子肝素钙酚妥拉明治疗肺心病顽固性心力衰竭临床观察 　　[摘要] 目的：探讨联合应用低分子肝素钙、酚妥拉明治疗肺心病顽固性心力衰竭的价值。方法：60例慢性肺心病患者随机分为观察组30例，对照组30例。对照组给予常规内科治疗；观察组在常规治疗基础上联合应用低分子肝素钙和酚妥拉明，每日1次，连用7～10 d，观察疗效。结果：观察组疗效明显优于对照组（P＜0.05）。结论：低分子肝素钙和酚妥拉明联合应用于治疗肺心病顽固性心力衰竭疗效良好，有较好的临床应用价值。 　　[关键词] 低分子肝素钙；酚妥拉明；肺心病；顽固性心力衰竭 　　[中图分类号] R541.5 [文献标识码]B [文章编号]1673-7210（2009）02（b）-036－０2 　　 　　Clinical observation in combination application of Low Molecular Heparin and Phentolamine in the treatment of pneumocardial disease with intractable heart failure 　　WU Yan-li 　　(The No.1 Peoples Hospital of Shangqiu City, Shangqiu476100, China) 　　[Abstract] Objective: To explore the effectiveness of the combination application of Low Molecular Heparin and Phentolamine in the treatment of pneumocardial disease with intractable heart failure. Methods: All 60 patients with chronic cardiopulmonary disease were randomly divided into observation group (30 cases)and control group (30 cases)．The patients in control group were administered routine medical treatment. The patients in trial group were administered combination Low Molecular Heparin and Phentolamine (qd，7-10 days)，on the base of routine medical treatment. The treatment effectiveness were observed. Results: There were obvious difference between observation group and control group (P＜0.05). Conclusion: There is well therapeutic effect in combination application of Low Molecular Heparin and Phentolamine in the treatment of pneumocardial disease with intractable heart failure, and better value in clinical application. 　　[Key words] Low Molecular Heparin; Phentolamine; Pneumocardial disease; Intractable heart failure 　　 　　肺心病并发顽固性心力衰竭是临床常见危重病症，内科常规应用抗生素、解痉平喘、止咳化痰、强心、利尿、吸氧等综合治疗，疗效不佳。我院2004年1月～2008年3月应用酚妥拉明与低分子肝素钙治疗肺心病心力衰竭60例，疗效满意，现报道如下： 　　1资料与方法 　　1.1一般资料 　　选择我院2004年1月～2008年3月住院的肺心病心衰患者60例，均符合慢性肺源性心脏病(肺心病)的诊断标准，心功能Ⅱ～Ⅳ级。随机分为观察组和对照组。观察组30例，男16例，女14例；年龄45～83岁，平均59.2岁；心功能Ⅱ级4例，心功能Ⅲ级16例，心功能Ⅳ级10例。对照组30例，男13例，女17例；年龄43～85岁，平均61.2岁；心功能Ⅱ级2例，心功能Ⅲ级20例，心功能Ⅳ级8例。两组患者性别、年龄、病程、心功能分级上差异无统计学意义（P＞