羌活饮片生产加工工艺规范化的研究.docVIP

羌活饮片生产加工工艺规范化的研究 　　[摘要] 该研究以羌活醇、异欧前胡素、挥发油和浸出物（水、醇）为研究对象，考察不同软化方法、切片厚度和干燥方法对羌活饮片质量的影响，采用归一距离评价法对实验数据进行分析。研究结果表明，不同软化、切制、干燥工艺会对羌活中5种成分的含量造成影响，羌活饮片的最佳加工工艺为羌活药材捡去沙石等非药用部位，除去霉变、虫蛀部分，用流动的饮用水抢水洗净，码放于润药池中，采用闷润法进行软化，每1 kg药材每隔2 h喷洒1/8量水，药材上部用洁净湿润的棉布覆盖，闷润12 h至药材内外软硬程度适宜后切厚片（2～4 mm），于50 ℃鼓风干燥4 h，期间翻动2次。该工艺切实可行，为羌活饮片生产加工的标准化提供了实验依据，对羌活饮片质量的提高具有重要意义。 　　[关键词] 羌活； 软化； 切制； 干燥； 加工工艺 　　[Abstract] Notopterol， isoimperatorin， volatile oil and extract （water and ethanol） were used as the research objects in this study to investigate the effects of different softening method， slice thickness and drying methods on the quality of Notopterygii Rhizoma et Radix slices， and the experimental data were analyzed by homogeneous distance evaluation method. The results showed that different softening， cutting and drying processes could affect the content of five components in Notopterygii Rhizoma et Radix incisum. The best processing technology of Notopterygii Rhizoma et Radix slices was as follows： non-medicinal parts were removed； mildewed and rot as well as moth-eaten parts were removed； washed by the flowing drinking water； stacked in the drug pool； moistening method was used for softening， where 1/8 volume of water was sprayed for every 1 kg of herbs every 2 h； upper part of herbs covered with clean and moist cotton， and cut into thick slices （2-4 mm） after 12 h moistening until appropriate softness， then received blast drying for 4 h at 50 ℃， and turned over for 2 times during the drying. The process is practical and provides the experimental basis for the standardization of the processing of Notopterygii Rhizoma et Radix， with great significance to improve the quality of Notopterygii Rhizoma et Radix slices. 　　[Key words] Notopterygii Rhizoma et Radix； softening； cutting； drying； processing technology 　　羌活?樯⌒慰浦参锴蓟?Notopterygium incisum Ting ex H. T. Chang或宽叶羌活 N. franchetii H. de Boiss.的干燥根茎和根，具有解表散寒，祛风除湿，止痛的功能，用于风寒感冒，头痛项强，风湿痹痛，肩背酸痛[1]。2015年版《中国药典》将挥发油、浸出物、羌活醇和异欧前胡素作为羌活质量评价指标，现代研究亦认为羌活醇