阿卡波糖治疗2型糖尿病临床的的疗效观察.docVIP

阿卡波糖治疗2型糖尿病临床的的疗效观察 　　【摘 要】目的：观察阿卡波糖治疗2型糖尿病的临床疗效。方法：选取2016.04～2017.11来我院就诊的120例2型糖尿病患者为研究对象，根据治疗方式的不同，分为观察组和对照组，每组60例。观察组给予二甲双胍+阿卡波糖，对照组给予二甲双胍，比较两组患者空腹和餐后2h血糖恢复正常时间、治疗实施总时间、糖尿病相关指标及临床疗效。结果：观察组患者空腹和餐后2h血糖恢复正常时间、治疗实施总时间显著低于对照组，差异有统计学，P0.05；治疗后观察组糖化血红蛋白（HbA1c）、餐后2h血糖（2hPC）、空腹血糖（FPC）水平显著低于对照组，差异有统计学，P0.05；观察组临床有效率为96.67%，显著高于对照组的78.33%，差异有统计学，P0.05。结论：阿卡波糖治疗2型糖尿病的临床疗效显著，值得临床推广应用。 　　【关键词】阿卡波糖；2型糖尿病；临床疗效 　　Abstract Objective： To observe the clinical efficacy of acarbose in the treatment of type 2 diabetes mellitus.Methods： A total of 120 type 2 diabetic patients treated in our hospital from 2016.04 to 2017.11 were selected as study subjects.According to the different treatment methods， they were divided into observation group and control group， 60 cases in each group.The observation group was treated with metformin plus acarbose， and the control group was given metformin.The fasting and postprandial blood glucose recovery time the total duration of treatment， diabetes-related indicators and clinical efficacy were compared.Results： The fasting blood glucose and postprandial blood glucose recovery time at 2h were observed in the observation group， and the total duration of the treatment was significantly lower than that of the control group （P 0.05）.After treatment， the levels of HbA1c， 2h postprandial blood glucose （2hPC ）， Fasting blood glucose （FPC） levels were significantly lower than the control group， the difference was statistically significant （P 0.05）.The clinical effective rate in the observation group was 96.67%， which was significantly higher than that in the control group （78.33%， P 0.05）.Conclusion： The clinical of efficacy acarbose treatment of type 2 diabetes is significant， worthy of clinical application. 　　Key words： acarbose； type 2 diabetes mellitus； clinical efficacy 　　【中?D分类号】R587.1 【文献标识码】A 【文章编号】1672-3783（2018）02-03-0-01 　　糖尿病（diabetes mellitus，DM）[1，2]是由于胰岛素分泌缺陷或作用障碍所致的以一组代谢性疾病，以高血糖为特征，持续高血糖和代谢紊乱会导致眼、心[3]、肾、神经系统等全身多组织器官的损害[4]。近年来，随着社会的发展，生活水平