不同年龄段女性卵巢癌临床治疗剖析.docVIP

不同年龄段女性卵巢癌临床治疗剖析 　　【摘要】 目的 比较中年与老年女性卵巢肿瘤的临床特点、治疗及预后的差异,并分析预后相关因素。方法 回顾性分析辽河油田中心医院诊治的70例卵巢恶性肿瘤患者,将其分为中年组(45～60岁)40例、老年组(≥65岁)30例,对其临床症状、术后残瘤灶大小、化疗及预后分别进行对比分析,并进行预后相关因素分析。结果 中、老年女性3年生存率分别为72.3%、60.5%。单因素分析显示青、老年女性3年生存率差异有统计学意义。行最佳减瘤术及完成化疗者,中年组所占比例显著较老年组多(分别为 86.5%vs.41.3%,70%vs.49%)。结论 中年女性预后较老年女性好,卵巢癌预后与年龄有关,但年龄不是预后的重要因素。残瘤灶大小及化疗是影响预后的独立因素。 　　【关键词】 年龄;中年妇女;老年妇女;卵巢癌 　　 　　Clinical analysis of treatment for different aged women With ovarian cancer 　　 　　LV Pin,HE Ling,CHAI Hui-xia. 　　Department of Gynaecology and Obstetrics,the Central Hospital of Liaohe Oil Field, Liao Ning, Panjin 124000,China 　　 　　【Abstract】 Objective To compare clinical pathological characteristics, therapeutics and prognosisbetween middle-aged and elderly women with ovarian cancer,and to analyze its prognostic factors.Methods Retrospective study of 70 cases with ovarian cancer admitted in our hospital,we classified the all patients into 2 groups,the middle-aged group had 40 patienis (45~60 age),and the elderly group had 30 patients.Compared their Clinical symptom , postoperative residual tumor size,chemotherapy between two groups and their prognosis, and to analyze its prognostic factors.Results 3-years survival of middle-aged and elderly women were 72.3%、60.5%. Univariate analysis showed that middle-aged women had a significantly better prognosis than that of elderly middle women who aceepted optimal debulking surgery and completed chemotherapy,was significantly more than elderly women (86.5%vs.41.3%,70%vs.49% respectively) .Conclusion Prognosis of middle-aged women is better than that of the elderly, The prognosis of ovarian eaneer is related with age,but the age is not an important factor in the prognostic factors.Postoperative residual tumor size is a independent prognostic factors. 　　【Key words】 Age; Middle-aged women; Eldly women; Ovarian cancer 　　 　　作者单位:124000辽河油田中心医院妇产科 　　 　　卵巢癌是妇科恶性肿瘤的首要致死病因[1],发病率居妇科恶性肿瘤的第三位,然而病死率居其首位,因此有“妇科恶魔”之称。美国癌症协会2004年 (ACS2004)的一项统计结果显示:仅2004年一年中,新诊断