儿童急性下呼吸道感染7种常见病毒检出情况剖析.docVIP

儿童急性下呼吸道感染7种常见病毒检出情况剖析 　　doi：10.3969/j.issn.1007-614x.2014.17.73 　　摘要目的：探讨急性下呼吸道感染患儿7种常见病毒检出情况。方法：2012年4月-2013年4月收治急性下呼吸道感染患儿1 361例，采用直接免疫荧光法对其鼻咽深部分泌物标本7种常见病毒进行检测，分析检测结果呈阳性的患儿年龄构成和感染情况。结果：本次研究患儿中7种常见呼吸道病毒检测呈阳性341例，阳性率25.05%。不同性别患儿间阳性率差异无统计学意义（P=0.753）；其中PIVⅢ病毒的感染例数最多（128例），其次为RSV病毒感染（122例）。单种病毒感染和混合病毒感染的患儿当中均为PIVⅢ病毒感染率最高，其次为RSV病毒。年龄≤3岁组检测阳性率明显高于4～7岁组和≥8岁组，差异均有统计学意义（P0.05）。结论：PIVⅢ是本地区儿童呼吸道疾病感染的首要病原，该病在≤3岁婴幼儿中发病率最高，且多合并其他病毒感染。 　　关键词儿童呼吸道感染常见病毒 　　Analysis of 7 kinds of common virus detection in children with acute lower respiratory tract infection 　　Guo Liying 　　Department of Clinical Laboratory，the People’s Hospital of Hebi City，Henan 458030 　　AbstractObjective：To investigate the detection of 7 kinds of common virus in children with acute lower respiratory tract infection.Methods：1 361 children diagnosed with acute lower respiratory tract infection were selected from April 2012 to April 2013.Detecte 7 kinds of common virus of nasopharyngeal secretion specimens in deep using direct immunofluorescence method，to analyse the age composition and infection in children with positive results.Results：341 cases in this study had positive results in the detection of 7 kinds of common respiratory viruses，and the positive rate was 25.05%.The positive rate of children had no significant difference between different gender（P=0.753）.PIV virus infection account for greatest number of cases in 341 cases with virus infection（128 cases），followed by RSV virus infection（122 cases）.PIVⅢvirus infection rate was the highest both in single virus infection and in mixed infection，followed by RSV virus.The positive rate in the age≤3 years old group was higher than in the 4～7 years old group and the age≥8 years old group，and the differences were statistically significant（P0.05）. Conclusion：PIV III is the primary pathogen of local respiratory diseases in children infected.The highest incidence of this disease was in infants and children under 3 years old，and always combined with other virus