规范化治疗妊娠期糖尿病36例临床剖析.docVIP

规范化治疗妊娠期糖尿病36例临床剖析 　　[摘要] 目的 探讨妊娠期糖尿病的孕期规范化治疗对妊娠结局的影响。方法 选取该院诊断及治疗、分娩的72例妊娠期糖尿病患者作为研究对象，通过计算机软件把72例妊娠期糖尿病患者随机分成两组，观察组和对照组各36例，给予研究组妊娠期糖尿病患者规范化治疗，给予对照组常规治疗，对比两组孕妇临床资料、妊娠结局及围产儿结局。结果 对照组妊娠期糖尿病孕妇体重增加及剖宫产率显著高于研究组孕妇，两组在妊娠期高血压、羊水过多、胎膜早破、酮症酸中毒、产后出血、巨大儿、胎儿窘迫、新生儿低血糖、高胆红素血症等方面比较差异有统计学意义（P0.05）。结论 妊娠期糖尿病孕期规范化治疗，可明显降低母婴并发症的发生率，改善妊娠结局，甚至达到正常孕妇水平，值得临床应用。 　　[关键词] 妊娠期糖尿病；孕期规范化；治疗妊娠结局 　　[中图分类号] R714.256 [文献标识码] A [文章编号] 1674-0742（2015）08（b）-0040-03 　　[Abstract] Objective To explore the effect of standardized treatment for gestational diabetes mellitus on pregnant outcomes. Methods 72 patients with gestational diabetes mellitus who underwent diagnosis， treatment and delivery in our hospital were selected as the research object and divided randomly， by computer software， into observation group and control group with 36 in each. Standardized treatment and routine treatment were performed in them respectively. The clinical data， pregnant outcomes， and perinatal outcomes were compared between the two groups. Results The rate of weight gain and cesarean section rate were obviously higher in the control group than in the observation group. In addition， in the aspects of hypertensive disorders in pregnancy， polyhydramnios， premature rupture of membranes， ketoacidosis， postpartum hemorrhage， giant baby， fetal distress， neonatal hypoglycemia， hyperbilirubinemia etc， there were statistically significant differences between the two groups（P0.05）. Conclusion Standardized treatment for gestational diabetes mellitus can reduce maternal and neonatal complications and improve pregnant outcomes. Therefore it is worthy of clinical application. 　　[Key words] Gestational diabetes mellitus； Standardized treatment； Pregnant outcomes 　　妊娠期糖尿病（GDM）是妊娠期首次发生或发现的糖代谢异常伴明显的代谢障碍，通常发生在妊娠中晚期，国内GDM发生率大约为1%～5%[1]。近年来随着人们生活方式和膳食营养结构的改变，GDM的患病率逐年增加，目前已成为妊娠期并发症中最突出的，GDM的早期诊断及有效管理是围生医学的重要课题。该研究回顾性分析2014年4月―2015年3月该院诊断、治疗及分娩的36例GDM患者的临床资料，并随机抽取同期血糖正常的36例分娩孕妇作为对照组，旨在探讨GDM的孕期规范化治疗对妊娠结局的影响，现报道如下。 　　1 资料与方法 　　1.1 一般资料