重组人PTP1B的原核高效表达及TFLC的体外抑制剂试验.PDF

212 2009 6 4 3 Chin Med Biotechnol, June 2009, Vol. 4, No. 3 DOI:10.3969/cmba.j.issn.1673-713X.2009.03.010 ·· PTP1B TFLC p210Bcr-Abl TYK2Janus kinase2 JNK2 PTP1B PTP1B rhPTP1B PTP1B pGEX-hPTP1B E.coliDH5α PTP1B rhPTP1B GST rhPTP1B 4- [3] PTP1B pNPP-Na2 leptin rhPTP1B rhPTP1B 2 [4] Na VO Litsea Coreana 3 4 TFLC rhPTP1B rhPTP1B 34 2.0 mmol/L IPTG 10 h GST 2003 [5] 35 rhPTP1B 2004 TFLC rhPTP1B total flavonoids of Litsea Coreana TFLC rhPTP1B TFLC rhPTP1B 242717 1 [6] 2 PTP1B , 2009, 4(3):212-218 2 1B PTP1B