青年人肺癌217例临床及病理特征剖析.docVIP

青年人肺癌217例临床及病理特征剖析 　　【摘要】 目的 探讨青年人原发性支气管肺癌临床及病理特点。方法 对2007年1月至2008年12月我院收治217例40岁以下的原发性支气管肺癌患者进行回顾性分析。结果 青年人肺癌男女比例为1.47∶1,病理类型以腺癌最多占42.4%,其次鳞癌为29%及小细胞肺癌为15.7%。TNM分期以Ⅲb-Ⅳ期居多占71.9%,手术切除率低。结论 青年肺癌病理类型以腺癌最多,其次为鳞癌及小细胞肺癌,确诊时多为晚期,预后差。重视青年患者的肺部表现,及时行相应检查,有助于肺癌的早期诊断及治疗。 　　【关键词】 青年人;肺癌;病理;临床分析 　　 　　The analysis of clinical and pathological characteristics of 217 young patients with lung cancer 　　 　　ZHOU Hui, WANG An-lan, YI Qing,et al. 　　Hunan Tumour Hospital, Changsha, 410013,China 　　 　　【Abstract】 Objective To study the clinical and pathological characteristics of young patients with primary bronchogenic carcinoma of lung.Methods 217 young lung cancer patients (40 years old or younger) who had detailed clinical data were studied retrospectively from Jan 2007 to Dec 2008.Results The occurrence ratio of male to female was 1.47:1. Adenocarcinoma was accounted for 42.4% and it was the main histological type of lung cancer in youth. The secondary was squamous carcinoma (29%) , followed by small cell lung cancer (15.7% ). The disease at advanced stage was most manifested ( about 71.9%) in young patients.The rate of acceptable surgical resection was low.Conclusion In these young patients, adenocarcinoma is the main histological type, and the secondary was squamous carcinoma and small cell lung cancer . The disease at advanced stage is common, and the prognosis is poor. It should be paid more attention to the symptoms of chest while doing some essential examination so as to make the confirmation of the diagnosis and conduct reasonable treatment in early stage. 　　【Key words】 Young;Lung cancer;Pathology;C linical analysis 　　 　　? 　　作者单位:410013湖南省肿瘤医院内科(周辉 汪安兰 易青 徐建华);中南大学湘雅三医院肿瘤科(曹培国) 　　 　　目前,国内外文献大多将40岁以下的肺癌患者列为青年人肺癌[1];近年来,青年肺癌的发患者数有上升的趋势。2007年1月至2008年12月, 我们对217例40岁以下青年肺癌患者的临床资料及病理特点进行回顾性分析, 旨在提高对青年肺癌的认识,探讨青年人肺癌的临床病理特点。 　　1 临床资料 　　1.1 一般资料 在3985例肺癌患者中,40岁以下的肺癌患者217例,占5.44%。其中男129例,女88例,男女之比为1.47∶1;平均年龄(33.46±5.8)岁。217例患者中有吸烟史110例,均为男性。 　　1.2 临床症状咳嗽146例(67.3%)、胸痛55