分子印迹光子晶体聚合物在氨基酸手性识别传感中的应用-化学专业论文.docx

ABSTRACT The incorporation of molecularly imprinted materials into photonic crystals, which is named molecularly imprinted photonic polymer, is an ideal sensing platform wherein analyte recognition and an analyte-dependent transduction methodology are simultaneously realized. When molecularly imprinted photonic polymers recognize the imprinted molecules, the volume of imprinted polymers will continuously change with the changes of the external environment. At the same time, the modulation of the photonic crystal lattice parameter leads to a change of the Bragg diffraction peak, which results in a color change of the imprinted polymers that can be observe by naked eyes. The change of diffraction peak can be measured by fiber optic spectrometer in order to achieve the quantitative determination for the analytes. In the present work, L-pyroglutamic acid imprinted photonic polymers have been prepared by using different functional monomers and polymerization modes. The chiral and non-chiral recognition of glutamate were studied by investigating its selectivity and sensitivity using the intelligent molecularly imprinted photonic polymer as sensor.The main content are as follows： L-pyroglutamic acid imprinted photonic polymers were thermally polymerized with acrylamide and methyl methacrylate. The selectivity of the imprinted photonic polymers to the imprinted molecular has been studied. It was found the molecularly imprinted sensor has a very good selectivity for L-pyroglutamic acid when compared to D-pyroglutamic acid, L-phenylalanine, L-threonine and L-alanine. Linear relationship was found between the Δλ and the concentration of imprinted molecule, and a color change of the imprinted polymers can be observed by naked eyes. The concentration of L-pyroglutamic acid in monosodium glutamate samples was detected using such imprinted polymers. Thermopolymerization and photopolymerization methods were used for preparation of L-pyroglutamic acid imprinted photonic pol